ArticleEndocrinology and metabolism (Seoul, Korea)2015
Electrolyte Imbalance in Patients with Sheehan's Syndrome.
Article in Endocrinology and metabolism (Seoul, Korea), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 15 citations in OpenAlex.
- Late-onset Sheehan's syndrome: a major diagnostic challenge-a case report.Journal of medical case reports · 2025Article
- Sheehan syndrome: a current approach to a dormant disease.Pituitary · 2025Review
- Partial Sheehan's syndrome with abdominal tuberculosis presented with pancytopenia and fluctuating thyroid profile: a case report.Annals of medicine and surgery (2012) · 2023Article
- A Rare Case of Postpartum Panhypopituitarism Without Imaging Evidence of Sheehan's Syndrome.Cureus · 2022Article
- A rare endocrine cause of electrical storm - a case report.European heart journal. Case reports · 2017Article
- A rare endocrine cause of ventricular tachycardia: a case series of two patients and a literature review.Cardiovascular journal of AfricaReview
- Acute parkinsonism in a patient with myxedema crisis: A case report.Medicine internationalArticle
- Clinical, Endocrine, Metabolic Profile, and Bone Health in Sheehan's Syndrome.Indian journal of endocrinology and metabolismArticle
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe investigated the prevalence of electrolyte imbalance and the relationship between serum electrolyte and anterior pituitary hormone levels in patients with Sheehan's syndrome.
methodsIn a retrospective study, we investigated 78 patients with Sheehan's syndrome. We also included 95 normal control subjects who underwent a combined anterior pituitary hormone stimulation test and showed normal hormonal responses.
resultsIn patients with Sheehan's syndrome, the serum levels of sodium, potassium, ionized calcium, magnesium, and inorganic phosphate were significantly lower than those in control subjects. The prevalence of hyponatremia, hypokalemia, hypocalcemia, hypomagnesemia, and hypophosphatemia in patients with Sheehan's syndrome was 59.0% (n=46), 26.9% (n=21), 35.9% (n=28), 47.4% (n=37), and 23.1% (n=18), respectively. Levels of sodium and ionized calcium in serum were positively correlated with levels of all anterior pituitary hormones (all P<0.05). Levels of potassium in serum were positively correlated with adrenocorticotrophic hormone (ACTH) and growth hormone (GH) levels (all P<0.05). Levels of inorganic phosphate in serum were positively correlated with levels of thyroid-stimulating hormone, prolactin, and GH (all P<0.05), and levels of magnesium in serum were positively correlated with delta ACTH (P<0.01).
conclusionElectrolyte imbalance was common in patients with Sheehan's syndrome. Furthermore, the degree of anterior pituitary hormone deficiency relates to the degree of electrolyte disturbance in patients with this disease.
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