ArticleHuman brain mapping2016
Desynchronization of fronto-temporal networks during working memory processing in autism.
Article in Human brain mapping, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 68 citations in OpenAlex.
- Neural dysfunctions associated with atypical memory in ASD: an ALE meta-analysis.Frontiers in psychiatry · 2026Pooled it
- Oscillatory activity underlying cognitive performance in children and adolescents with autism: a systematic review.Frontiers in human neuroscience · 2024Pooled it
- Brain correlates of declarative memory atypicalities in autism: a systematic review of functional neuroimaging findings.Molecular autism · 2023Pooled it
- Is functional brain connectivity atypical in autism? A systematic review of EEG and MEG studies.PloS one · 2017Pooled it
- Balanced bifrontal transcranial direct current stimulation enhances working memory in adults with high-functioning autism: a sham-controlled crossover study.Molecular autism · 2017Trial
- Can Music Therapy Improve Cognition in Dementia as Measured with Magnetoencephalography: A Hypothesis Study.Biomedicines · 2026Article
- The Nodding syndrome cerebrospinal fluid proteome: a lens into neurodevelopmental failure consistent with environmentally triggeredFrontiers in molecular neuroscience · 2026Article
- Contrast subgraphs catch patterns of altered functional connectivity in autism spectrum disorder.Scientific reports · 2025Article
- Association between theta-band resting-state functional connectivity and declarative memory abilities in children.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- What Ability Can Predict Mathematics Performance in Typically Developing Preschoolers and Those with Autism Spectrum Disorder?Journal of autism and developmental disorders · 2023Article
- Article
- Multi-classifier fusion based on belief-value for the diagnosis of autism spectrum disorder.Frontiers in human neuroscience · 2023Article
- Constructing high-order functional networks based on hypergraph for diagnosis of autism spectrum disorders.Frontiers in neuroscience · 2023Article
- Effects of working memory load on frontal connectivity in children with autism spectrum disorder: a fNIRS study.Scientific reports · 2022Article
- Abnormal Degree Centrality in Children with Low-Function Autism Spectrum Disorders: A Sleeping-State Functional Magnetic Resonance Imaging Study.Neuropsychiatric disease and treatment · 2022Article
- Multi-View Feature Enhancement Based on Self-Attention Mechanism Graph Convolutional Network for Autism Spectrum Disorder Diagnosis.Frontiers in human neuroscience · 2022Article
- Automatic classification of autism spectrum disorder in children using cortical thickness and support vector machine.Brain and behavior · 2021Article
- Synchronizing Brain Rhythms to Improve Cognition.Annual review of medicine · 2021Review
- Article
- Alpha connectivity and inhibitory control in adults with autism spectrum disorder.Molecular autism · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundMounting evidence suggests that autism is a network disorder, characterized by atypical brain connectivity, especially in the context of high level cognitive processes such as working memory (WM). Accordingly, atypical WM processes have been related to the social and cognitive deficits observed in children with autism spectrum disorder (ASD).
methodsWe used magnetoencephalography (MEG) to investigate connectivity differences during a high memory load (2-back) WM task between 17 children with ASD and 20 age-, sex-, and IQ-matched controls.
resultsWe identified reduced inter-regional alpha-band (9-15 Hz) phase synchronization in children with ASD during the WM task. Reduced WM-related brain synchronization encompassed fronto-temporal networks (ps < 0.04 corrected) previously associated with challenging high-level conditions (i.e. the left insula and the anterior cingulate cortex (ACC)) and memory encoding and/or recognition (i.e. the right middle temporal gyrus and the right fusiform gyrus). Additionally, we found that reduced connectivity processes related to the right fusiform were correlated with the severity of symptoms in children with ASD, suggesting that such atypicalities could be directly related to the behavioural deficits observed. DISCUSSION: This study provides new evidence of atypical long-range synchronization in children with ASD in fronto-temporal areas that crucially contribute to challenging WM tasks, but also emotion regulation and social cognition processes. Thus, these results support the network disorder hypothesis of ASD and argue for a specific pathophysiological contribution of brain processes related to working memory and executive functions on the symptomatology of autism.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.