ArticleeLife2015
Human blindsight is mediated by an intact geniculo-extrastriate pathway.
Article in eLife, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
71 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Neural activities during the Processing of unattended and unseen emotional faces: a voxel-wise Meta-analysis.Brain imaging and behavior · 2022Pooled it
- Pathway-dependent brain stimulation responses indicate motion processing integrity after stroke.Brain : a journal of neurology · 2025Trial
- Boosting Learning Efficacy with Noninvasive Brain Stimulation in Intact and Brain-Damaged Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Trial
- From error to evidence: blindsight in the making†.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Generalisation of training-induced recovery in occipital stroke: neurochemical and fMRI correlates.bioRxiv : the preprint server for biology · 2026Article
- Acute requirement for the hippocampus in putatively conscious vision revealed by a mouse model of blindsight.Current biology : CB · 2026Article
- Causal disconnectomics of motion perception networks: insights from transcranial magnetic stimulation-induced BOLD responses.The Journal of physiology · 2026Article
- Static Visual Agnosia Following Awake Resection of a Left Frontal Low-Grade Glioma: A Case Report of Ventral Stream Network Disruption ("Astatopsia").Reports (MDPI) · 2025Article
- In vivo parcellation of the human superior colliculus from brain-wide probabilistic connectivity.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Pathways Mediating Blindsight After V1 Injury: A Systematic Review of Human and Monkey Studies.Basic and clinical neuroscience · 2025Review
- Review
- Voxel-Based Lesion-Symptom Mapping Localizes Residual Visual Function in Hemianopia.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Assessing higher-order visual functions: seeing beyond a flat earth.Dementia & neuropsychologia · 2025Review
- Tractometry of Human Visual White Matter Pathways in Health and Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- A clinico-anatomical dissection of the magnocellular and parvocellular pathways in a patient with the Riddoch syndrome.Brain structure & function · 2024Article
- Parallel Streams of Direct Corticogeniculate Feedback from Mid-level Extrastriate Cortex in the Macaque Monkey.eNeuro · 2024Article
- Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 2 registered report.Brain communications · 2024Article
- Rehabilitating homonymous visual field deficits: white matter markers of recovery-stage 1 registered report.Brain communications · 2024Article
- Preserved motion perception and the density of cortical projections to V5 in homonymous hemianopia.Brain communications · 2024Article
- Evidence for adaptive myelination of subcortical shortcuts for visual motion perception in healthy adults.Human brain mapping · 2023Article
11 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
Although damage to the primary visual cortex (V1) causes hemianopia, many patients retain some residual vision; known as blindsight. We show that blindsight may be facilitated by an intact white-matter pathway between the lateral geniculate nucleus and motion area hMT+. Visual psychophysics, diffusion-weighted magnetic resonance imaging and fibre tractography were applied in 17 patients with V1 damage acquired during adulthood and 9 age-matched controls. Individuals with V1 damage were subdivided into blindsight positive (preserved residual vision) and negative (no residual vision) according to psychophysical performance. All blindsight positive individuals showed intact geniculo-hMT+ pathways, while this pathway was significantly impaired or not measurable in blindsight negative individuals. Two white matter pathways previously implicated in blindsight: (i) superior colliculus to hMT+ and (ii) between hMT+ in each hemisphere were not consistently present in blindsight positive cases. Understanding the visual pathways crucial for residual vision may direct future rehabilitation strategies for hemianopia patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.