Trial reportMedicine and science in sports and exercise2016
Low-Active Male Adolescents: A Dose Response to High-Intensity Interval Training.
Trial report in Medicine and science in sports and exercise, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Process evaluation of school-based high-intensity interval training interventions for children and adolescents: a systematic review and meta-analysis of randomized controlled trials.BMC public health · 2024Pooled it
- School-based high-intensity interval training programs in children and adolescents: A systematic review and meta-analysis.PloS one · 2022Pooled it
- Effects of 8-week strength training on basal hormone levels, sex hormone binding globulin, insulin-like growth factor binding protein-3, oxidative stress markers, and IL-6 levels in adolescent athletes.Hormones (Athens, Greece) · 2025Trial
- Effects of different game-based physical activity programs on body composition in Chinese preschool children.Frontiers in public health · 2025Trial
- The effect of 4 weeks of high-intensity interval training and 2 weeks of detraining on cardiovascular disease risk factors in male adolescents.Experimental physiology · 2023Trial
- Comparable Effects of High-Intensity Interval Training and Prolonged Continuous Exercise Training on Abdominal Visceral Fat Reduction in Obese Young Women.Journal of diabetes research · 2017Trial
- Assessing the sustained impact of a school-based obesity prevention program for adolescent boys: the ATLAS cluster randomized controlled trial.The international journal of behavioral nutrition and physical activity · 2016Trial
- Trial
- Weekly frequency of school-based HIIT improves adiposity and fitness in children with obesity.iScience · 2026Article
- Dose-Response Effects of High-Intensity Interval Training on Body Fat, Blood Pressure, and Cardiorespiratory Fitness in Adolescents: A School-Based Randomized Controlled Trial with Responder Analysis.Journal of functional morphology and kinesiology · 2025Article
- The Impact of Modified Tabata Training on Segmental Fat Accumulation, Muscle Mass, Muscle Thickness, and Physical and Cardiorespiratory Fitness in Overweight and Obese Participants: A Randomized Control Trial.Sports (Basel, Switzerland) · 2025Article
- Effect of eight-week high-intensity interval training versus moderate-intensity continuous training programme on body composition, cardiometabolic risk factors in sedentary adolescents.Frontiers in physiology · 2024Article
- The Prevalence of Responders and Non-Responders for Body Composition, Resting Blood Pressure, Musculoskeletal, and Cardiorespiratory Fitness after Ten Weeks of School-Based High-Intensity Interval Training in Adolescents.Journal of clinical medicine · 2023Article
- The Mediating Effect of Physical Fitness and Dietary Intake on the Relationship of Physical Activity with Body Composition in High School Students.International journal of environmental research and public health · 2022Article
- Effects of aerobic exercise combined with resistance training on health-related physical fitness in adolescents: A randomized controlled trial.Journal of exercise science and fitness · 2022Article
- Article
- Effects of Aerobic Exercise and High-Intensity Interval Training on the Mental Health of Adolescents Living in Poverty: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2022Article
- Effect of two-weeks of school-based sprint training on physical fitness, risk factors for cardiometabolic diseases and cognitive function in adolescent girls: A randomized controlled pilot trial.Frontiers in sports and active living · 2022Article
- The effect of HIIT on body composition, cardiovascular fitness, psychological well-being, and executive function of overweight/obese female young adults.Frontiers in psychology · 2022Article
- High-intensity interval training in high-school physical education classes: Study protocol for a randomized controlled trial.Contemporary clinical trials communications · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHigh-intensity interval training (HIIT) is a potential alternative to traditionally recommended steady state exercise for providing health benefits in adolescents, yet its dose-response relationship in this cohort remains unclear, as does its translatability to real-world, nonclinical settings. The present study adopts a novel dose-response design to investigate the effects of undertaking 8 wk of HIIT on the cardiometabolic health of low-active male adolescents.
methodsTwenty-six male adolescents (age 16 ± 1 yr), identified as low active by nonparticipation in structured sport and physical education classes, were randomly assigned to one of five treatment groups. Corresponding with their group numbers (1-5), participants completed a number of HIIT "sets," which consisted of 4 repeated bouts of 20-s near-maximal exertion interspersed with 10-s passive recovery. Participants performed two HIIT sessions and one resistance training session each week for 8 wk. Baseline and follow-up health measures consisted of peak oxygen uptake (V˙O2peak) with an incremental ramp test to volitional exhaustion; body composition (including visceral fat mass, body fat, and lean tissue mass) with dual-energy x-ray absorptiometry; and lipid profile, glucose, insulin, and interleukin-6 from blood analysis. All health outcomes were analyzed as percentage changes, and data were modeled using a quadratic function to explore dose-response relationships.
resultsSignificant improvements were observed for V˙O2peak (∼6%), body fat percentage (∼4%), visceral fat mass (∼10%), and waist circumference-to-height ratio (∼3%), but there was no clear effect of dose across groups.
conclusionsLow-active adolescent males performing a single HIIT set twice weekly, in addition to one resistance training session, gained meaningful improvements in fitness and body composition. Performing additional HIIT sets provided no additional improvements to those of the lowest dose in this study.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.