Evidence map›Paper›PMID 26484866›Full record

ArticlePLoS neglected tropical diseases2015

RETRACTED: Mansonella, including a Potential New Species, as Common Parasites in Children in Gabon.

Gaël Mourembou, Florence Fenollar, Jean Bernard Lekana-Douki, Angelique Ndjoyi Mbiguino, Sydney Maghendji Nzondo, Pierre Blaise Matsiegui, Rella Zoleko Manego, Cyrille Herve Bile Ehounoud, Fadi Bittar, Didier Raoult and 1 more

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
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  8. Large-scale production ofFrontiers in tropical diseases · 2024
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  11. Molecular surveillance detects high prevalence of the neglected parasitemedRxiv : the preprint server for health sciences · 2023
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  13. Whole genome analysis of two sympatric humanFrontiers in cellular and infection microbiology · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 2 countries.

Gaël MourembouAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France; Ecole Doctorale Régionale d'Afrique Centrale, Franceville, Gabon.
Florence FenollarAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Jean Bernard Lekana-DoukiUnité de Parasitologie Médicale (UPARAM) CIRMF, Franceville, Gabon; Département de Parasitologie Mycologie et de Médecine Tropicale, Université des Science de la Santé, Libreville, Gabon.
Angelique Ndjoyi MbiguinoDépartement de Microbiologie, Laboratoire National de Référence IST/sida, Faculté de Médecine, Université des Sciences de la Santé, Libreville, Gabon.
Sydney Maghendji NzondoUnité de Parasitologie Médicale (UPARAM) CIRMF, Franceville, Gabon.
Pierre Blaise MatsieguiCentre de Recherches Médicales de la Ngounié, Fougamou, Gabon.
Rella Zoleko ManegoCentre de Recherches Médicales de la Ngounié, Fougamou, Gabon.
Cyrille Herve Bile EhounoudAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Fadi BittarAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Didier RaoultAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Oleg MediannikovAix-Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France.
Centre International de Recherches Médicales de Franceville · GAInstitut de Recherche pour le Développement · FRUniversité des Sciences de la Santé · GAAix-Marseille Université · FRCentre National de la Recherche Scientifique · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLike other tropical African countries, Gabon is afflicted by many parasitic diseases, including filariases such as loiasis and mansonellosis. This study aimed to assess the prevalence of these two filarial diseases in febrile and afebrile children using quantitative real-time PCR and standard PCR assays coupled with sequencing. METHODOLOGY/PRINCIPAL

findingsDNA from blood specimens of 1,418 Gabonese children (1,258 febrile and 160 afebrile) were analyzed. Overall, filarial DNA was detected in 95 (6.7%) children, including 67 positive for M. perstans (4.7%), which was the most common. M. perstans was detected in 61/1,258 febrile children (4.8%) and 6/160 afebrile children (3.8%, P = 0.6). Its prevalence increased statistically with age: 3.5%, 7.7% and 10.6% in children aged ≤ 5, 6-10 and 11-15 years, respectively. M. perstans prevalence was significantly higher in Koulamoutou and Lastourville (12% and 10.5%, respectively) than in Franceville and Fougamou (2.6% and 2.4%, respectively). Loa loa was detected in seven febrile children including one co-infection with M. perstans. Finally, 21 filarial DNA positive were negative for M. perstans and Loa loa, but ITS sequencing could be performed for 12 and allowed the identification of a potential new species of Mansonella provisionally called "DEUX". Mansonella sp. "DEUX" was detected only in febrile children. CONCLUSIONS/SIGNIFICANCE: Further study should be performed to characterize Mansonella sp. "DEUX" and evaluate the clinical significance of mansonellosis in humans.

Indexed as

AdolescentAge FactorsAnimalsBloodChildChild, PreschoolCluster AnalysisDNA, HelminthDNA, Ribosomal SpacerFemaleGabonHumansInfantLoaLoiasisMaleDNA, HelminthDNA, Ribosomal Spacer

Identifiers

PMID26484866
PMCPMC4618925
OpenAlexW2138330449

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.