Evidence map›Paper›PMID 26484778›Full record

ArticleEmerging infectious diseases2015

Shigella Infections in Household Contacts of Pediatric Shigellosis Patients in Rural Bangladesh.

Christine Marie George, Shahnawaz Ahmed, Kaisar A Talukder, Ishrat J Azmi, Jamie Perin, R Bradley Sack, David A Sack, O Colin Stine, Lauren Oldja, Mohammad Shahnaij and 9 more

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  9. IgG Serum Antibodies toVaccines · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Christine Marie George
Shahnawaz Ahmed
Kaisar A Talukder
Ishrat J Azmi
Jamie Perin
R Bradley Sack
David A Sack
O Colin Stine
Lauren Oldja
Mohammad Shahnaij
Subhra Chakraborty
Tahmina Parvin
Sazzadul Islam Bhuyian
Edward Bouwer
Xiaotong Zhang
Trisheeta N Hasan
Sharmin J Luna
Fatema Akter
Abu S G Faruque

Funding

EPIDEMIOLOGY &ECOLOGY OF VIBRIO CHOLERAE IN BANGLADESHR01AI039129 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SACK, DAVID A · 1996 to 2014
$15.2M
Identifying Transmission Routes for Cholera among Household Contacts of Cases K01AI110526 · NIAID · JOHNS HOPKINS UNIVERSITY · PI GEORGE, CHRISTINE MARIE · 2015 to 2017
$410k
NIAID NIH HHS K01 AI110526NIAID NIH HHS R01 AI039129
6 · The paper itself

Abstract

To examine rates of Shigella infections in household contacts of pediatric shigellosis patients, we followed contacts and controls prospectively for 1 week after the index patient obtained care. Household contacts of patients were 44 times more likely to develop a Shigella infection than were control contacts (odds ratio 44.7, 95% CI 5.5-361.6); 29 (94%) household contacts of shigellosis patients were infected with the same species and serotype as the index patient's. Pulsed-field gel electrophoresis showed that 14 (88%) of 16 with infected contacts had strains that were indistinguishable from or closely related to the index patient's strain. Latrine area fly counts were higher in patient households compared with control households, and 2 patient household water samples were positive for Shigella. We show high susceptibility of household contacts of shigellosis patients to Shigella infections and found environmental risk factors to be targeted in future interventions.

Indexed as

Family CharacteristicsBangladeshChild, PreschoolDisease OutbreaksDysentery, BacillaryFemaleHumansInfantInfant, NewbornMaleRisk FactorsRural PopulationShigellaantibacterial drugsbacteriaBangladeshchilddysenteryenteric infectionshouseflieshouseholdshygieneinsect vectorssanitationShigellashigellosisvector-borne infectionswater quality

Identifiers

PMID26484778
PMCPMC4622242

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.