Evidence map›Paper›PMID 26484733›Full record

ReviewMethods (San Diego, Calif.)2016

Building cell models and simulations from microscope images.

Robert F Murphy

Abstract readReview
In one paragraph

Review in Methods (San Diego, Calif.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Learning Morphological, Spatial, and Dynamic Models of Cellular Components.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Image-derived generative modeling of pseudo-macromolecular structures - towards the statistical assessment of Electron CryoTomography template matching.BMVC : proceedings of the British Machine Vision Conference. British Machine Vision Conference · 2018
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Robert F MurphyComputational Biology Department, Center for Bioimage Informatics, and Departments of Biological Sciences, Biomedical Engineering and Machine Learning, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA, USA; Freiburg Institute for Advanced Studies and Faculty of Biology, Albert Ludwig University of Freiburg, Germany. Electronic address: murphy@cmu.edu.

Funding

TrainingP41GM103712 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FAEDER, JAMES · 2012 to 2021
$16.3M
Image-derived Spatiotemporal Models of Cellular Organization and PerturbationR01GM090033 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI MURPHY, ROBERT F, ROHDE, GUSTAVO KUNDE · 2010 to 2018
$2.4M
BUILDING AND VALIDATING LOCATION PROTEOMICS DATABASESR01GM075205 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI MURPHY, ROBERT F · 2007 to 2011
$1.8M
NIGMS NIH HHS GM075205NIGMS NIH HHS GM090033NIGMS NIH HHS GM103712NIGMS NIH HHS P41 GM103712NIGMS NIH HHS R01 GM075205NIGMS NIH HHS R01 GM090033
6 · The paper itself

Abstract

The use of fluorescence microscopy has undergone a major revolution over the past twenty years, both with the development of dramatic new technologies and with the widespread adoption of image analysis and machine learning methods. Many open source software tools provide the ability to use these methods in a wide range of studies, and many molecular and cellular phenotypes can now be automatically distinguished. This article presents the next major challenge in microscopy automation, the creation of accurate models of cell organization directly from images, and reviews the progress that has been made towards this challenge.

Indexed as

Image Processing, Computer-AssistedMachine LearningModels, BiologicalPattern Recognition, AutomatedCell ShapeComputational BiologyComputer SimulationHeLa CellsHumansMicroscopy, FluorescenceSoftwareCell organizationCell shapeComputational biologyGenerative modelsImage-based modeling

Identifiers

PMID26484733
PMCPMC4766043

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.