ReviewPediatric research2016
Maternal and pediatric health and disease: integrating biopsychosocial models and epigenetics.
Review in Pediatric research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Maternal depression in Latinas and child socioemotional development: A systematic review.PloS one · 2020Pooled it
- Racial Discrimination and Adverse Birth Outcomes: An Integrative Review.Journal of midwifery & women's health · 2016Pooled it
- DHA Supplementation During Pregnancy Enhances Maternal Vagally Mediated Cardiac Autonomic Control in Humans.The Journal of nutrition · 2023Trial
- Future of Families: Cardiovascular Health Among Young Adults Cohort Study: Rationale, Key Questions, Study Design, and Participant Characteristics.Journal of the American Heart Association · 2025Article
- Homelessness in pregnancy: life course factors and mental health in the context of COVID-19.Frontiers in psychiatry · 2025Article
- Investigating the role of relationship satisfaction and paternal psychological distress during pregnancy on offspring health in early life.BJPsych open · 2023Article
- Towards the multileveled and processual conceptualisation of racialised individuals in biomedical research.Synthese · 2023Article
- Maternal Social Risk, Gestational Age at Delivery, and Cognitive Outcomes among Adolescents Born Extremely Preterm.Paediatric and perinatal epidemiology · 2022Article
- Cardiometabolic Pregnancy Complications in Association With Autism-Related Traits as Measured by the Social Responsiveness Scale in ECHO.American journal of epidemiology · 2022Article
- The Association between Racial Discrimination, Posttraumatic Stress Disorder, and Cardiovascular-Related Conditions Among Non-Hispanic Blacks: Results from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III).Journal of racial and ethnic health disparities · 2022Article
- Prenatal stress dysregulates resting-state functional connectivity and sensory motifs.Neurobiology of stress · 2021Article
- Biopsychosocial Factors during the Perinatal Period: Risks, Preventative Factors, and Implications for Healthcare Professionals.International journal of environmental research and public health · 2021Review
- Exploring the relationship between maternal prenatal stress and brain structure in premature neonates.PloS one · 2021Article
- Temporally and sex-specific effects of maternal perinatal stress on offspring cortical gyrification and mood in young adulthood.Human brain mapping · 2020Article
- Food Addiction and Psychosocial Adversity: Biological Embedding, Contextual Factors, and Public Health Implications.Nutrients · 2020Review
- Factors Associated with Unplanned Primary Cesarean Birth: Secondary Analysis of the Listening to Mothers in California Survey.BMC pregnancy and childbirth · 2020Article
- Maternal Prenatal Stress Is Associated With Altered Uncinate Fasciculus Microstructure in Premature Neonates.Biological psychiatry · 2020Article
- Article
- Prenatal Stress, Mood, and Gray Matter Volume in Young Adulthood.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Environmental Exposures, the Epigenome, and African American Women's Health.Journal of urban health : bulletin of the New York Academy of Medicine · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The concepts of allostasis (stability through adaptation) and accumulated life stress (McEwen's allostatic load) aim to understand childhood and adult outcomes. Chronic malnutrition, changes in social condition, and adverse early-life experiences may program phenotypes and contribute to long-lasting disease risk. However, integration of life course approaches, social and economic contexts, and comparison among different biopsychosocial models has not generally been explored. This review critically examines the literature and evaluates recent insights into how environmental stress can alter lifelong hypothalamic-pituitary-adrenal axis and immune system responsiveness and induce metabolic and neurodevelopmental maladaptation. Models of biopsychosocial stress overlap but may consider different conditions. Concepts include allostasis, which incorporates hormonal responses to predictable environmental changes, and Geronimus's "weathering," which aims to explain how socially structured, repeated stress can accumulate and increase disease vulnerability. Weathering emphasizes roles of internalized/interpersonal racism in outcomes disparities. For Mexican immigrants and Mexican Americans, the "acculturation" framework has proven especially useful to explore disparities, including preterm birth and neuropsychiatric risks in childhood. Complexities of stress assessments and recent research into epigenetic mechanisms mediating effects of physical, nutritional, psychological, and social stress are reviewed.
Indexed as
Identifiers
26484619What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.