Evidence map›Paper›PMID 26484423›Full record

ArticleEpidemiology (Cambridge, Mass.)2016

Evaluation of Selection Bias in an Internet-based Study of Pregnancy Planners.

Elizabeth E Hatch, Kristen A Hahn, Lauren A Wise, Ellen M Mikkelsen, Ramya Kumar, Matthew P Fox, Daniel R Brooks, Anders H Riis, Henrik Toft Sorensen, Kenneth J Rothman

Abstract readEvaluation Study
In one paragraph

Article in Epidemiology (Cambridge, Mass.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

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5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Elizabeth E HatchFrom the aDepartment of Epidemiology, Boston University School of Public Health, Boston, MA; bDepartment of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; and cRTI Health Solutions, Durham, NC.
Kristen A Hahn
Lauren A Wise
Ellen M Mikkelsen
Ramya Kumar
Matthew P Fox
Daniel R Brooks
Anders H Riis
Henrik Toft Sorensen
Kenneth J Rothman

Funding

BURPPE:BU Reproductive, Perinatal, and Pediatric Epidemiology Training ProgramT32HD052458 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI WERLER, MARTHA M. · 2007 to 2016
$2.0M
NICHD NIH HHS T32 HD052458
6 · The paper itself

Abstract

Selection bias is a potential concern in all epidemiologic studies, but it is usually difficult to assess. Recently, concerns have been raised that internet-based prospective cohort studies may be particularly prone to selection bias. Although use of the internet is efficient and facilitates recruitment of subjects that are otherwise difficult to enroll, any compromise in internal validity would be of great concern. Few studies have evaluated selection bias in internet-based prospective cohort studies. Using data from the Danish Medical Birth Registry from 2008 to 2012, we compared six well-known perinatal associations (e.g., smoking and birth weight) in an internet-based preconception cohort (Snart Gravid n = 4,801) with the total population of singleton live births in the registry (n = 239,791). We used log-binomial models to estimate risk ratios (RRs) and 95% confidence intervals (CIs) for each association. We found that most results in both populations were very similar. For example, maternal obesity was associated with an increased risk of delivering a macrosomic infant in Snart Gravid (RR = 1.5; 95% CI: 1.2, 1.7) and the total population (RR = 1.5; 95% CI: 1.45, 1.53), and maternal smoking of >10 cigarettes per day was associated with a higher risk of low birth weight (RR = 2.7; 95% CI: 1.2, 5.9 vs. RR = 2.9; 95% CI: 2.6, 3.1) in Snart Gravid and the total population, respectively. We cannot be certain that our results would apply to other associations or different populations. Nevertheless, our results suggest that recruitment of reproductive aged women via the internet may be no more prone to selection bias than traditional methods of recruitment.

Indexed as

InternetPatient SelectionSelection BiasAdolescentAdultDenmarkFemaleFollow-Up StudiesHumansInfant, NewbornLinear ModelsPregnancyPregnancy ComplicationsProspective StudiesRegistriesReproducibility of Results

Identifiers

PMID26484423
PMCPMC4819248

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.