Evidence map›Paper›PMID 26484357›Full record

ArticleOpen forum infectious diseases2015

Stx-Producing Shigella Species From Patients in Haiti: An Emerging Pathogen With the Potential for Global Spread.

Miranda D Gray, Susan R Leonard, David W Lacher, Keith A Lampel, Meer T Alam, J Glenn Morris, Afsar Ali, Patrick T LaBreck, Anthony T Maurelli

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open forum infectious diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Distribution and characterization of Shiga toxin converting temperate phages carried by Shigella flexneri in Hispaniola.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2018
    Article
  4. A Brief History ofEcoSal Plus · 2018
    Review
  5. IDCases · 2017
    Article
  6. Comparative Genomic and Phylogenetic Analysis of a Shiga Toxin ProducingFrontiers in cellular and infection microbiology · 2017
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Miranda D GrayDepartment of Microbiology and Immunology , Uniformed Services University of the Health Sciences , Bethesda.
Susan R LeonardUS Food and Drug Administration, Center for Food Safety and Nutrition , Laurel, Maryland.
David W LacherUS Food and Drug Administration, Center for Food Safety and Nutrition , Laurel, Maryland.
Keith A LampelUS Food and Drug Administration, Center for Food Safety and Nutrition , Laurel, Maryland.
Meer T AlamUniversity of Florida, Emerging Pathogens Institute, ; Department of Environmental and Global Health, College of Public Health and Health Professions , University of Florida , Gainesville.
J Glenn MorrisUniversity of Florida, Emerging Pathogens Institute.
Afsar AliUniversity of Florida, Emerging Pathogens Institute, ; Department of Environmental and Global Health, College of Public Health and Health Professions , University of Florida , Gainesville.
Patrick T LaBreckDepartment of Microbiology and Immunology , Uniformed Services University of the Health Sciences , Bethesda.
Anthony T MaurelliDepartment of Microbiology and Immunology , Uniformed Services University of the Health Sciences , Bethesda.
Uniformed Services University of the Health Sciences · USCenter for Food Safety and Applied Nutrition · USUniversity of Florida · USUnited States Food and Drug Administration · US

Funding

TEMPERATURE REGULATION OF SHIGELLA VIRULENCE GENESR01AI024656 · NIAID · HENRY M. JACKSON FDN FOR THE ADV MIL/MED · PI MAURELLI, ANTHONY T · 1989 to 2013
$3.8M
Cholera Transmission in Gressier Region, HaitiR01AI097405 · NIAID · UNIVERSITY OF FLORIDA · PI MORRIS, JOHN GLENN · 2012 to 2015
$2.7M
NIAID NIH HHS R01 AI024656NIAID NIH HHS R01 AI097405
6 · The paper itself

Abstract

Shiga toxins (Stx) are commonly produced by Shigella dysenteriae serotype 1 and Stx-producing Escherichia coli. However, the toxin genes have been detected in additional Shigella species. We recently reported the emergence of Stx-producing Shigella in travelers in the United States and France who had recently visited Hispaniola (Haiti and the Dominican Republic). In this study, we confirm this epidemiological link by identifying Stx-producing Shigella from Haitian patients attending clinics near Port-au-Prince. We also demonstrate that the bacteriophage encoding Stx is capable of dissemination to stx-negative Shigella species found in Haiti, suggesting that Stx-producing Shigella may become more widespread within that region.

Indexed as

bacteriophageHaitiShiga toxinShigella

Identifiers

PMID26484357
PMCPMC4606844
OpenAlexW2097445344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.