Transcriptomic study on the impact of temporomandibular joint internal derangement in the condylar cartilage of rabbits.

Shuhua Wang, Gaoli Xu, Liquan Deng, Zhiyuan Gu

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In one paragraph

Article in Genomics data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

Integrated bioinformatics analysis of differentially expressed genes in the temporomandibular joint internal derangement.Clinical and experimental dental research · 2023
Article

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5 · Who and what money

Authors and funding

4 authors.

Shuhua WangSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.

Gaoli XuDepartment of Oral and Maxillofacial Surgery, School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.

Liquan DengKey Laboratory of Stomatology, School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.

Zhiyuan GuSchool of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Internal derangement (ID) in the temporomandibular joint (TMJ) compromises a group of clinical problems, and holds a relative high prevalence in populations. However, the temporal genomic change in gene expression of condylar cartilage during continuous ID remains unclear. Here we reported the differentially expressed gene pattern in condylar cartilage of rabbits with ID from 1 to 8 weeks by microarray analysis. The whole genome project was deposited at GenBank under the accession PRJNA278127. The microarray analysis showed that 6478 genes have more than two-fold changes among all the tested transcripts. Many inflammation gene increased rapidly in the early stage while decrease later. On the contrary, the bone construction related genes showed a low level at first and increased at later period in the ID progression. Besides, the current study found some genes such as HLA2G, which had never been reported, might be relevant with ID.

Indexed as

Animal modelGenomic expressionInternal derangementTemporomandibular jointTranscriptomic study

Identifiers

PMID26484287

DOI10.1016/j.gdata.2015.06.034

PMCPMC4583689

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LicenceCC BY-NC-ND

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