Evidence map›Paper›PMID 26484159›Full record

ArticleGenomics data2015

Kuwaiti population subgroup of nomadic Bedouin ancestry-Whole genome sequence and analysis.

Sumi Elsa John, Gaurav Thareja, Prashantha Hebbar, Kazem Behbehani, Thangavel Alphonse Thanaraj, Osama Alsmadi

Open access · goldAbstract read
In one paragraph

Article in Genomics data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sumi Elsa JohnDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Gaurav TharejaDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Prashantha HebbarDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Kazem BehbehaniDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Thangavel Alphonse ThanarajDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Osama AlsmadiDasman Diabetes Institute, P.O. Box 1180, Dasman 15462, Kuwait.
Dasman Diabetes Institute · KW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kuwaiti native population comprises three distinct genetic subgroups of Persian, "city-dwelling" Saudi Arabian tribe, and nomadic "tent-dwelling" Bedouin ancestry. Bedouin subgroup is characterized by presence of 17% African ancestry; it owes it origin to nomadic tribes of the deserts of Arabian Peninsula and North Africa. By sequencing whole genome of a Kuwaiti male from this subgroup at 41X coverage, we report 3,752,878 SNPs, 411,839 indels, and 8451 structural variations. Neighbor-joining tree, based on shared variant positions carrying disease-risk alleles between the Bedouin and other continental genomes, places Bedouin genome at the nexus of African, Asian, and European genomes in concordance with geographical location of Kuwait and Peninsula. In congruence with participant's medical history for morbid obesity and bronchial asthma, risk alleles are seen at deleterious SNPs associated with obesity and asthma. Many of the observed deleterious 'novel' variants lie in genes associated with autosomal recessive disorders characteristic of the region.

Indexed as

Arabian PeninsulaIntergenome distancesKuwaiti populationNomadic Bedouin ancestry“Tent-dwelling” BedouinsWhole genome sequence

Identifiers

PMID26484159
PMCPMC4535864
OpenAlexW1985547787

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.