Evidence map›Paper›PMID 26484151›Full record

ArticleGenomics data2015

Multipotent human stromal cells isolated from cord blood, term placenta and adult bone marrow show distinct differences in gene expression pattern.

Nicholas Matigian, Gary Brooke, Faten Zaibak, Tony Rossetti, Katarina Kollar, Rebecca Pelekanos, Celena Heazlewood, Alan Mackay-Sim, Christine A Wells, Kerry Atkinson

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genomics data, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Nicholas MatigianAustralian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia ; Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia.
Gary BrookeMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Faten ZaibakMurdoch Children's Research Institute, The University of Melbourne, Royal Children's Hospital, Parkville, Victoria, 3052, Australia.
Tony RossettiMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Katarina KollarMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Rebecca PelekanosMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Celena HeazlewoodMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
Alan Mackay-SimEskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia.
Christine A WellsAustralian Institute for Bioengineering and Nanotechnology, University of Queensland, Brisbane, 4072, Australia ; Eskitis Institute for Drug Discovery, National Centre for Adult Stem Cell Research, Griffith University, Brisbane, 4111, Australia ; The Institute for Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, The University of Glasgow, Scotland, G12 8TA, UK.
Kerry AtkinsonMater Medical Research Institute, University of Queensland, Woolloongabba, Brisbane, 4102, Australia.
The University of Queensland · AUGriffith University · AURoyal Children's Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multipotent mesenchymal stromal cells derived from human placenta (pMSCs), and unrestricted somatic stem cells (USSCs) derived from cord blood share many properties with human bone marrow-derived mesenchymal stromal cells (bmMSCs) and are currently in clinical trials for a wide range of clinical settings. Here we present gene expression profiles of human cord blood-derived unrestricted somatic stem cells (USSCs), human placental-derived mesenchymal stem cells (hpMSCs), and human bone marrow-derived mesenchymal stromal cells (bmMSCs), all derived from four different donors. The microarray data are available on the ArrayExpress database (www.ebi.ac.uk/arrayexpress) under accession number E-TABM-880. Additionally, the data has been integrated into a public portal, www.stemformatics.org. Our data provide a resource for understanding the differences in MSCs derived from different tissues.

Indexed as

Mesenchymal stem cellsMesenchymal stromal cellsMultipotent human stromal cells

Identifiers

PMID26484151
PMCPMC4535874
OpenAlexW2170607557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.