Evidence map›Paper›PMID 26484128›Full record

ArticleGenomics data2014

Gene expression in rat models for inter-generational transmission of islet dysfunction and obesity.

Ruby C Y Lin, Sheau-Fang Ng, Margaret J Morris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genomics data, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Ruby C Y LinAsbestos Diseases Research Institute, NSW, 2139 Sydney, Australia ; School of Biotechnology and Biomolecular Sciences, University of New South Wales, NSW 2052, Australia.
Sheau-Fang NgDepartment of Paediatrics, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Universiti Kebangsaan Malaysia, 56000 Kuala Lumpur, Malaysia ; Department of Pharmacology, School of Medical Sciences, University New South Wales, NSW 2052, Australia.
Margaret J MorrisDepartment of Pharmacology, School of Medical Sciences, University New South Wales, NSW 2052, Australia.
UNSW Sydney · AUUniversity Kebangsaan Malaysia Medical Centre · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paternal high fat diet (HFD) consumption triggers unique gene signatures, consistent with premature aging and chronic degenerative disorders, in both white adipose tissue (RpWAT) and pancreatic islets of daughters. In addition to published data in Nature, 2010, 467, 963-966 (GSE: 19877, islet) and FASEB J 2014, 28, 1830-1841 (GSE: 33551, RpWAT), we describe here additional details on systems-based approaches and analysis to develop our observations. Our data provides a resource for exploring the complex molecular mechanisms that underlie intergenerational transmission of obesity.

Indexed as

Gene signaturesHigh fat dietIntergenerational transmissionIslet dysfunctionPaternal transmission

Identifiers

PMID26484128
PMCPMC4536069
OpenAlexW1991076553

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.