Evidence map›Paper›PMID 26484120›Full record

ArticleGenomics data2014

Genome-wide mRNA and miRNA expression data analysis to screen for markers involved in sarcomagenesis in human chondrosarcoma cell lines.

Biju Issac, Karina Galoian, Toumy Guettouche, Loida Navarro, H Thomas Temple

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genomics data, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Biju IssacBiostatistics and Bioinformatics Core/Division of Bioinformatics, Sylvester comprehensive Cancer Center, University of Miami, 1550 NW 10th Ave, Fox 304A, Miami, FL 33136, USA.
Karina GaloianDepartment of Orthopaedic Surgery, Miller School of Medicine, University of Miami, 1600 NW 10th Ave, S 8012, Miami, FL 33136, USA.
Toumy GuettoucheChildren's Hospital of Philadelphia, Center of Applied Genomics, 3615 Civic center Blvd, Philadelphia, PA 19104-4318, USA.
Loida NavarroOncogenomics Core, Sylvester Comprehensive Cancer Center, University of Miami, 1501 NW 10th Ave, BRB 542 B.02, Miami FL 33136, USA.
H Thomas TempleDepartment of Orthopaedic Surgery and University of Miami Tissue Bank Division, Miller School of Medicine, University of Miami, 1400 NW 12th Ave, UMH, East Bldg 4036, Miami, FL 33136, USA.
University of Miami · USChildren's Hospital of Philadelphia · USSylvester Comprehensive Cancer Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genes and miRNAs involved in sarcomagenesis related pathways are unknown and therefore signaling events leading to mesenchymal cell transformation to sarcoma are poorly elucidated. Exiqon and Illumina microarray study on human chondrosarcoma JJ012 and chondrocytes C28 cell lines to compare and analyze the differentially expressed miRNAs and their gene targets was recently published in the Journal Tumor Biology in 2014. Here we describe in details the contents and quality controls for the miRNA and gene expression data associated with the study that is relevant to this dataset.

Indexed as

BioinformaticsHuman chrondrosarcomaMicroarraymiRNAsmRNA expressionPCA, principal component analysisSD, standard deviation

Identifiers

PMID26484120
PMCPMC4536178
OpenAlexW2151947590

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.