ReviewJournal of sexually transmitted diseases2015
Human Papilloma Virus Associated Squamous Cell Carcinoma of the Head and Neck.
Review in Journal of sexually transmitted diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 45 citations in OpenAlex.
- Genomic landscape of virus-associated cancers.Nature communications · 2025Article
- Skin Lesions Caused by HPV-A Comprehensive Review.Biomedicines · 2024Review
- Epidemiology and Risk Factors of Actinic Keratosis. What is New for The Management for Sun-Damaged Skin.Dermatology practical & conceptual · 2024Review
- The Effects of ML385 on Head and Neck Squamous Cell Carcinoma: Implications for NRF2 Inhibition as a Therapeutic Strategy.International journal of molecular sciences · 2024Article
- Article
- CREB1 activation promotes human papillomavirus oncogene expression and cervical cancer cell transformation.Journal of medical virology · 2023Article
- The Pathogenesis of Giant Condyloma Acuminatum (Buschke-Lowenstein Tumor): An Overview.International journal of molecular sciences · 2022Review
- Identification of HPV16-p16Epigenetics · 2021Article
- Immuno-Oncological Biomarkers for Squamous Cell Cancer of the Head and Neck: Current State of the Art and Future Perspectives.Cancers · 2021Review
- The Predictive Model of Oral Squamous Cell Survival Carcinoma: A Methodology of Validation.BioMed research international · 2021Article
- TRIM21 Polymorphisms are associated with Susceptibility and Clinical Status of Oral Squamous Cell Carcinoma patients.International journal of medical sciences · 2021Article
- Gene Expression Profiling of MicroRNAs in HPV-Induced Warts and Normal Skin.Biomolecules · 2019Article
- A therapeutic approach towards microRNA29 family in vascular diabetic complications: A boon or curse?Journal of diabetes and metabolic disorders · 2019Article
- Association of low expression of E-cadherin and β-catenin with the progression of early stage human squamous cervical cancer.Oncology letters · 2019Article
- Optical biopsy of head and neck cancer using hyperspectral imaging and convolutional neural networks.Journal of biomedical optics · 2019Article
- International Endocervical Adenocarcinoma Criteria and Classification: Validation and Interobserver Reproducibility.The American journal of surgical pathology · 2019Article
- Diagnostic Algorithmic Proposal Based on Comprehensive Immunohistochemical Evaluation of 297 Invasive Endocervical Adenocarcinomas.The American journal of surgical pathology · 2018Article
- Development and validation of a radiomic signature to predict HPV (p16) status from standard CT imaging: a multicenter study.The British journal of radiology · 2018Article
- Detection of Human Papilloma Virus and Risk Factors among Patients with Head and Neck Squamous Cell Carcinoma Attending a Tertiary Referral Centre in South IndiaAsian Pacific journal of cancer prevention : APJCP · 2018Article
- STAT3 activation by E6 is essential for the differentiation-dependent HPV18 life cycle.PLoS pathogens · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral cancer is one of the commonest causes for mortality and morbidity with squamous cell carcinoma being the sixth most frequent malignant tumour worldwide. In addition to tobacco and alcohol, human papilloma virus (HPV) is associated with a proportion of head and neck cancers. As in cervical cancers, HPV types 16 and 18 are the cause of malignant transformation. HPV-positive cancers of head and neck have unique characteristics such as occurrence in a younger age group, distinct clinical and molecular features, and better prognosis as compared to HPV-negative carcinomas. They also possess the potential for prevention by using vaccination. The present review describes in detail the salient features of HPV associated oral squamous cell carcinoma (OSCC), its differences from HPV-negative OSCC, diagnostic features, and recent strategies in prevention and management.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.