ReviewWorld journal of gastrointestinal oncology2015
Immune cell interplay in colorectal cancer prognosis.
Review in World journal of gastrointestinal oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed.
- Aspirin's effect on macrophages beyond its chemopreventive role in inflammation and cancer.Inflammopharmacology · 2025Review
- The Immune Environment in Colorectal Adenoma: A Systematic Review.Biomedicines · 2025Review
- Prognostic significance of the Naples prognostic score in colorectal cancer patients undergoing curative resection: a propensity score matching analysis.BMC gastroenterology · 2023Article
- Curcumin and colorectal cancer: An update and current perspective on this natural medicine.Seminars in cancer biology · 2022Review
- Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer.Science advances · 2022Article
- Tumor-Associated Macrophages (TAMs) in Colorectal Cancer (CRC): From Mechanism to Therapy and Prognosis.International journal of molecular sciences · 2021Review
- Tumor-infiltrating lymphocytes in tissue material combined with systemic lymphocyte inflammation in patients with colorectal cancer.Molecular and clinical oncology · 2021Article
- Differential gene expression of tumor-infiltrating CD33Cancer immunology, immunotherapy : CII · 2021Article
- Extensive variability in the composition of immune infiltrate in different mouse models of cancer.Laboratory animal research · 2020Article
- Characterization of tumor-infiltrating immune cells in relation to microbiota in colorectal cancers.Cancer immunology, immunotherapy : CII · 2020Article
- Role of CC Chemokines Subfamily in the Platinum Drugs Resistance Promotion in Cancer.Frontiers in immunology · 2020Review
- Immune overdrive signature in colorectal tumor subset predicts poor clinical outcome.The Journal of clinical investigation · 2019Article
- Article
- Multiparametric analysis of colorectal cancer immune responses.World journal of gastroenterology · 2018Review
- Underlying Causes and Therapeutic Targeting of the Inflammatory Tumor Microenvironment.Frontiers in cell and developmental biology · 2018Review
- β7 integrins contribute to intestinal tumor growth in mice.PloS one · 2018Article
- Regulatory T-cell heterogeneity and the cancer immune response.Clinical & translational immunology · 2017Review
- Inclusion of BLIMP-1Cancer immunology, immunotherapy : CII · 2017Article
- Safety and antitumor activity of the anti-PD-1 antibody pembrolizumab in patients with advanced colorectal carcinoma.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immune response to colorectal cancer has proven to be a reliable measure of patient outcome in several studies. However, the complexity of the immune response in this disease is not well understood, particularly the interactions between tumour-associated cells and cells of the innate and adaptive immune system. This review will discuss the relationship between cancer associated fibroblasts and macrophages, as well as between macrophages and T cells, and demonstrate how each population may support or prevent tumour growth in a different immune environment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.