Evidence map›Paper›PMID 26483875›Full record

ReviewWorld journal of gastrointestinal oncology2015

Treatment of colorectal cancer in the elderly.

Monica Millan, Sandra Merino, Aleidis Caro, Francesc Feliu, Jordi Escuder, Tani Francesch

Registry-linked trialAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in World journal of gastrointestinal oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03097224 (Prehabilitation Before Surgery in Colorectal Cancer With Improved Fast Track Rehabilitation), which is not on this map. Cited by 70 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
70citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03097224 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Prehabilitation Before Surgery in Colorectal Cancer With Improved Fast Track Rehabilitation : Part 2

TypeinterventionalSponsorCliniques universitaires Saint-Luc- Université Catholique de LouvainRan2017 to 2020Enrolled40ConditionsColon Cancer, FragilityArmsPrehabilitation
3 · Its place in the literature

Who cites it

70 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. SEOM-GEMCAD-TTD clinical guidelines for the adjuvant treatment of colon cancer (2023).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2024
    Guideline
  2. Patient choice in colorectal cancer treatment - A systematic review and narrative synthesis of attribute-based stated preference studies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
    Pooled it
  3. Pooled it
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10 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Monica MillanMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Sandra MerinoMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Aleidis CaroMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Francesc FeliuMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Jordi EscuderMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.
Tani FranceschMonica Millan, Aleidis Caro, Francesc Feliu, Jordi Escuder, Colorectal Surgery Unit, Department of Surgery, Joan XXIII University Hospital, 43005 Tarragona, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer has a high incidence, and approximately 60% of colorectal cancer patients are older than 70, with this incidence likely increasing in the near future. Elderly patients (> 70-75 years of age) are a very heterogeneous group, ranging from the very fit to the very frail. Traditionally, these patients have often been under-treated and recruited less frequently to clinical trials than younger patients, and thus are under-represented in publications about cancer treatment. Recent studies suggest that fit elderly patients can be treated in the same way as their younger counterparts, but the treatment of frail patients with comorbidities is still a matter of controversy. Many factors should be taken into account, including fitness for treatment, the wishes of the patient and family, and quality of life. This review will focus on the existing evidence for surgical, oncologic, and palliative treatment in patients over 70 years old with colorectal cancer. Careful patient assessment is necessary in order to individualize treatment approach, and this should rely on a multidisciplinary process. More well-designed controlled trials are needed in this patient population.

Indexed as

ChemotherapyColorectal cancerElderlyPalliative careRadiotherapySurgery

Identifiers

PMID26483875
PMCPMC4606175

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.