ArticleFrontiers in physiology2015
Overexpression of GhWRKY27a reduces tolerance to drought stress and resistance to Rhizoctonia solani infection in transgenic Nicotiana benthamiana.
Article in Frontiers in physiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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35 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.
- Meta-analysis of the effects of overexpression of WRKY transcription factors on plant responses to drought stress.BMC genetics · 2019Pooled it
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- Laying the blueprint of abiotic stress tolerance: an analysis on the complexities of the stress matrix.Plant signaling & behavior · 2026Review
- Genome-wide identification of AP2/ERF transcription factors in Populus trichocarpa: structural analysis, expression patterns, and response to Melampsora larici-populina.BMC plant biology · 2026Article
- Early Plant Development as a Systems-Level Trait: Integrating Omics, Artificial Intelligence, and Emerging Biotechnologies.Plants (Basel, Switzerland) · 2026Review
- Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton.Functional & integrative genomics · 2025Article
- A review on strategies for crop improvement against drought stress through molecular insights.3 Biotech · 2024Review
- Advanced Biotechnological Interventions in Mitigating Drought Stress in Plants.Plants (Basel, Switzerland) · 2024Review
- QTLs and Candidate Loci Associated with Drought Tolerance Traits of Kaybonnet x ZHE733 Recombinant Inbred Lines Rice Population.International journal of molecular sciences · 2023Article
- Genome-Wide Identification and Expression Profiling of GlutathionePlants (Basel, Switzerland) · 2023Article
- Function analysis ofFrontiers in plant science · 2023Article
- Regulation of the regulators: Transcription factors controlling biosynthesis of plant secondary metabolites during biotic stresses and their regulation by miRNAs.Frontiers in plant science · 2023Review
- Genome-Wide Identification of theInternational journal of molecular sciences · 2022Article
- Role of WRKY Transcription Factors in Regulation of Abiotic Stress Responses in Cotton.Life (Basel, Switzerland) · 2022Review
- Inactivating transcription factor OsWRKY5 enhances drought tolerance through abscisic acid signaling pathways.Plant physiology · 2022Article
- WRKY transcription factors (TFs): Molecular switches to regulate drought, temperature, and salinity stresses in plants.Frontiers in plant science · 2022Review
- Overexpression of VvASMT1 from grapevine enhanced salt and osmotic stress tolerance in Nicotiana benthamiana.PloS one · 2022Article
- A salicylic acid inducible mulberry WRKY transcription factor, MiWRKY53 is involved in plant defence response.Plant cell reports · 2021Article
- GhWRKY1-like, a WRKY transcription factor, mediates drought tolerance in Arabidopsis via modulating ABA biosynthesis.BMC plant biology · 2021Article
- Regulatory Network of Cotton Genes in Response to Salt, Drought and Wilt Diseases (Frontiers in plant science · 2021Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
WRKY proteins constitute transcriptional regulators involved in various biological processes, especially in coping with diverse biotic and abiotic stresses. However, in contrast to other well-characterized WRKY groups, the functions of group III WRKY transcription factors are poorly understood in the economically important crop cotton (Gossypium hirsutum). In this study, a group III WRKY gene from cotton, GhWRKY27a, was isolated and characterized. Our data indicated that GhWRKY27a localized to the nucleus and that GhWRKY27a expression could be strongly induced by abiotic stresses, pathogen infection, and multiple defense-related signaling molecules. Virus-induced gene silencing (VIGS) of GhWRKY27a enhanced tolerance to drought stress in cotton. In contrast, GhWRKY27a overexpression in Nicotiana benthamiana markedly reduced plant tolerance to drought stress, as determined through physiological analyses of leaf water loss, survival rates, and the stomatal aperture. This susceptibility was coupled with reduced stomatal closure in response to abscisic acid and decreased expression of stress-related genes. In addition, GhWRKY27a-overexpressing plants exhibited reduced resistance to Rhizoctonia solani infection, mainly demonstrated by the transgenic lines exhibiting more severe disease symptoms, accompanied by attenuated expression of defense-related genes in N. benthamiana. Taken together, these findings indicated that GhWRKY27a functions in negative responses to drought tolerance and in resistance to R. solani infection.
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