Evidence map›Paper›PMID 26483686›Full record

ArticleFrontiers in pharmacology2015

From cumulative cultural transmission to evidence-based medicine: evolution of medicinal plant knowledge in Southern Italy.

Marco Leonti, Peter O Staub, Stefano Cabras, Maria Eugenia Castellanos, Laura Casu

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Leaves and Fruits Preparations ofAntibiotics (Basel, Switzerland) · 2021
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marco LeontiDepartment of Biomedical Sciences, University of Cagliari Cagliari, Italy.
Peter O StaubDepartment of Biomedical Sciences, University of Cagliari Cagliari, Italy.
Stefano CabrasDepartment of Mathematics and Informatics, University of Cagliari Cagliari, Italy ; Department of Statistics, Carlos III University of Madrid Getafe, Spain.
Maria Eugenia CastellanosDepartment of Informatics and Statistics, Rey Juan Carlos University Móstoles, Spain.
Laura CasuDepartment of Life and Environmental Sciences, University of Cagliari Cagliari, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In Mediterranean cultures written records of medicinal plant use have a long tradition. This written record contributed to building a consensus about what was perceived to be an efficacious pharmacopeia. Passed down through millennia, these scripts have transmitted knowledge about plant uses, with high fidelity, to scholars and laypersons alike. Herbal medicine's importance and the long-standing written record call for a better understanding of the mechanisms influencing the transmission of contemporary medicinal plant knowledge. Here we contextualize herbal medicine within evolutionary medicine and cultural evolution. Cumulative knowledge transmission is approached by estimating the causal effect of two seminal scripts about materia medica written by Dioscorides and Galen, two classical Greco-Roman physicians, on today's medicinal plant use in the Southern Italian regions of Campania, Sardinia, and Sicily. Plant-use combinations are treated as transmissible cultural traits (or "memes"), which in analogy to the biological evolution of genetic traits, are subjected to mutation and selection. Our results suggest that until today ancient scripts have exerted a strong influence on the use of herbal medicine. We conclude that the repeated empirical testing and scientific study of health care claims is guiding and shaping the selection of efficacious treatments and evidence-based herbal medicine.

Indexed as

causal effectcultural transmission and evolutionDe Materia Medicaevidence-basedglobalizationherbal medicinehistorical ethnopharmacologytraditional medical knowledge

Identifiers

PMID26483686
PMCPMC4588697

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