ArticleFrontiers in systems neuroscience2015
fMRI investigation of response inhibition, emotion, impulsivity, and clinical high-risk behavior in adolescents.
Article in Frontiers in systems neuroscience, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Multilevel Correlates of Youth Delinquent Behaviors: An Exploratory Analysis of Socioeconomic Context, Psychological Traits, and Task-Based Neural Activation in the ABCD Study.Social science insights and applications · 2025Article
- Existence of Dynamic Functional Connectivity Variations of Brain Networks in Psychogenic Non-Epileptic Seizures Through Resting-state Functional Magnetic Resonance Imaging.Journal of biomedical physics & engineering · 2025Article
- Brain Network Abnormalities in Obsessive-Compulsive Disorder: Insights from Edge Functional Connectivity Analysis.Behavioral sciences (Basel, Switzerland) · 2025Article
- Patient, supporter and primary healthcare professional perspectives on health risks in over 16s with attention deficit hyperactivity disorder (ADHD) in England: a national survey study.BMC health services research · 2024Article
- Modeling Suicidality with Multimodal Impulsivity Characterization in Participants with Mental Health Disorder.Behavioural neurology · 2023Article
- The effect of learning to drum on behavior and brain function in autistic adolescents.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Temporally dynamic neural correlates of drug cue reactivity, response inhibition, and methamphetamine-related response inhibition in people with methamphetamine use disorder.Scientific reports · 2022Article
- Medial Orbitofrontal De-Activation During Tonic Cold Pain Stimulation: A fMRI Study Examining the Opponent-Process Theory.Journal of pain research · 2020Article
- Behavioral and Neural Dysregulation to Social Rewards and Links to Internalizing Symptoms in Adolescents.Frontiers in behavioral neuroscience · 2019Article
- Prefrontal Cortex Activity Predicts Mental Fatigue in Young and Elderly Men During a 2 h "Go/NoGo" Task.Frontiers in neuroscience · 2018Article
- Setting the occasion for adolescent inhibitory control.Neurobiology of learning and memory · 2017Review
- Trait anxiety mediates the link between inferior frontal cortex volume and negative affective bias in healthy adults.Social cognitive and affective neuroscience · 2017Article
- Editorial: Reward- and aversion-related processing in the brain: translational evidence for separate and shared circuits.Frontiers in systems neuroscience · 2015Article
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High-risk behavior in adolescents is associated with injury, mental health problems, and poor outcomes in later life. Improved understanding of the neurobiology of high-risk behavior and impulsivity shows promise for informing clinical treatment and prevention as well as policy to better address high-risk behavior. We recruited 21 adolescents (age 14-17) with a wide range of high-risk behavior tendencies, including medically high-risk participants recruited from psychiatric clinics. Risk tendencies were assessed using the Adolescent Risk Behavior Screen (ARBS). ARBS risk scores correlated highly (0.78) with impulsivity scores from the Barratt Impulsivity scale (BIS). Participants underwent 4.7 Tesla functional magnetic resonance imaging (fMRI) while performing an emotional Go/NoGo task. This task presented an aversive or neutral distractor image simultaneously with each Go or NoGo stimulus. Risk behavior and impulsivity tendencies exhibited similar but not identical associations with fMRI activation patterns in prefrontal brain regions. We interpret these results as reflecting differences in response inhibition, emotional stimulus processing, and emotion regulation in relation to participant risk behavior tendencies and impulsivity levels. The results are consistent with high impulsivity playing an important role in determining high risk tendencies in this sample containing clinically high-risk adolescents.
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