Evidence map›Paper›PMID 26482956›Full record

ReviewTrends in plant science2016

CO2 Sensing and CO2 Regulation of Stomatal Conductance: Advances and Open Questions.

Cawas B Engineer, Mimi Hashimoto-Sugimoto, Juntaro Negi, Maria Israelsson-Nordström, Tamar Azoulay-Shemer, Wouter-Jan Rappel, Koh Iba, Julian I Schroeder

Abstract readReview
In one paragraph

Review in Trends in plant science, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 108 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
108citing papers in PubMed, 1 pooled it
30.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

108 citing papers in PubMed, 1 synthesis or guideline pooled it, 338 citations in OpenAlex.

  1. Pooled it
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  11. Antisense reduction in NADP-ME in the CThe New phytologist · 2026
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  17. A combination of morphological, biochemical and structural responses is required for desiccation tolerance inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Article
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  20. Synthetic crassulacean acid metabolism (SynCAM) for improving water-use efficiency in plants.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Review

48 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Cawas B EngineerDivision of Biological Sciences, Cell and Developmental Biology Section and Center for Food & Fuel for the 21st Century, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0116, USA.
Mimi Hashimoto-SugimotoDepartment of Biology, Faculty of Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Juntaro NegiDepartment of Biology, Faculty of Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Maria Israelsson-NordströmUmeå Plant Science Center, Department of Forest Genetics and Plant Physiology, Swedish University of Agricultural Sciences, SE-901 83 Umeå, Sweden.
Tamar Azoulay-ShemerDivision of Biological Sciences, Cell and Developmental Biology Section and Center for Food & Fuel for the 21st Century, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0116, USA.
Wouter-Jan RappelDivision of Biological Sciences, Cell and Developmental Biology Section and Center for Food & Fuel for the 21st Century, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0116, USA.
Koh IbaDepartment of Biology, Faculty of Sciences, Kyushu University, 744 Motooka, Nishi-ku, Fukuoka 819-0395, Japan.
Julian I SchroederDivision of Biological Sciences, Cell and Developmental Biology Section and Center for Food & Fuel for the 21st Century, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0116, USA. Electronic address: jischroeder@ucsd.edu.
University of California, San Diego · USKyushu University · JPSwedish University of Agricultural Sciences · SE

Funding

Yeast Genetics and Stress Response Genes-BiomedicalP42ES010337 · NIEHS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TUKEY, ROBERT H · 2000 to 2022
$69.8M
STRESS HORMONE SIGNAL TRANSDUCTION IN ARABIDOPSISR01GM060396 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHROEDER, JULIAN I · 2000 to 2023
$7.4M
NIEHS NIH HHS ES010337NIEHS NIH HHS P42 ES010337NIGMS NIH HHS GM060396NIGMS NIH HHS R01 GM060396
6 · The paper itself

Abstract

Guard cells form epidermal stomatal gas-exchange valves in plants and regulate the aperture of stomatal pores in response to changes in the carbon dioxide (CO2) concentration ([CO2]) in leaves. Moreover, the development of stomata is repressed by elevated CO2 in diverse plant species. Evidence suggests that plants can sense [CO2] changes via guard cells and via mesophyll tissues in mediating stomatal movements. We review new discoveries and open questions on mechanisms mediating CO2-regulated stomatal movements and CO2 modulation of stomatal development, which together function in the CO2 regulation of stomatal conductance and gas exchange in plants. Research in this area is timely in light of the necessity of selecting and developing crop cultivars that perform better in a shifting climate.

Indexed as

Abscisic AcidCalciumCarbon DioxidePhotosynthesisPlant StomataSignal TransductionAbscisic AcidCalciumCarbon Dioxideagricultureatmospheric carbon dioxideclimateguard cell signalingstomatal developmentstomatal movements

Identifiers

PMID26482956
PMCPMC4707055
OpenAlexW2196027445

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.