ArticleThe American journal of gastroenterology2015
Evolution of Screen-Detected Small (6-9 mm) Polyps After a 3-Year Surveillance Interval: Assessment of Growth With CT Colonography Compared With Histopathology.
Article in The American journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Imaging alternatives to colonoscopy: CT colonography and colon capsule. European Society of Gastrointestinal Endoscopy (ESGE) and European Society of Gastrointestinal and Abdominal Radiology (ESGAR) Guideline - Update 2020.European radiology · 2021Guideline
- Comparison of adenoma detection by colonoscopy between polypectomy performed during both insertion and withdrawal versus during withdrawal only: a multicenter, randomized, controlled trial.Surgical endoscopy · 2020Trial
- Molecular profiling of longitudinally observed small colorectal polyps: A cohort study.EBioMedicine · 2019Trial
- Novel colorectal cancer screening methods - opportunities and challenges.Nature reviews. Clinical oncology · 2025Review
- Water exchange technique improves colonoscopy in patients with spinal cord injury: Results of a matched cohort study.Endoscopy international open · 2024Article
- Quantification of Serum Metabolites in Early Colorectal Adenomas Using Isobaric Labeling Mass Spectrometry.Journal of proteome research · 2023Article
- Long term outcomes of colon polyps with high grade dysplasia following endoscopic resection.BMC gastroenterology · 2020Article
- Similar Adenoma Detection Rates in Colonoscopic Procedures of Patients with Spinal Cord Injury Compared to Controls.Digestive diseases and sciences · 2020Article
- Conserved serum protein biomarkers associated with growing early colorectal adenomas.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- The Natural History of Colorectal Polyps: Overview of Predictive Static and Dynamic Features.Gastroenterology clinics of North America · 2018Review
- Lesions of All Types Exist in Colon Polyps of All Sizes.The American journal of gastroenterology · 2018Article
- CT colonography: role in FOBT-based screening programs for colorectal cancer.Clinical journal of gastroenterology · 2017Review
- Polyp Resection - Controversial Practices and Unanswered Questions.Clinical and translational gastroenterology · 2017Article
- Screening and Surveillance of Colorectal Cancer Using CT Colonography.Current treatment options in gastroenterology · 2017Review
- Molecular stool testing as an alternative for surveillance colonoscopy: a cross-sectional cohort study.BMC cancer · 2017Observational
- CT colonography for population screening of colorectal cancer: hints from European trials.The British journal of radiology · 2016Review
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Authors and funding
12 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesVolumetric growth assessment has been proposed for predicting advanced histology at surveillance computed tomography (CT) colonography (CTC). We examined whether is it possible to predict which small (6-9 mm) polyps are likely to become advanced adenomas at surveillance by assessing volumetric growth.
methodsIn an invitational population-based CTC screening trial, 93 participants were diagnosed with one or two 6-9 mm polyps as the largest lesion(s). They were offered a 3-year surveillance CTC. Participants in whom surveillance CTC showed lesion(s) of ≥6 mm were offered colonoscopy. Volumetric measurements were performed on index and surveillance CTC, and polyps were classified into growth categories according to ±30% volumetric change (>30% growth as progression, 30% growth to 30% decrease as stable, and >30% decrease as regression). Polyp growth was related to histopathology.
resultsBetween July 2012 and May 2014, 70 patients underwent surveillance CTC after a mean surveillance interval of 3.3 years (s.d. 0.3; range 3.0-4.6 years). In all, 33 (35%) of 95 polyps progressed, 36 (38%) remained stable, and 26 (27%) regressed, including an apparent resolution in 13 (14%) polyps. In 68 (83%) of the 82 polyps at surveillance, histopathology was obtained; 15 (47%) of 32 progressing polyps were advanced adenomas, 6 (21%) of 28 stable polyps, and none of the regressing polyps.
conclusionsThe majority of 6-9 mm polyps will not progress to advanced neoplasia within 3 years. Those that do progress to advanced status can in particular be found among the lesions that increased in size on surveillance CTC.
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