Trial reportPediatrics2015
Promoting HPV Vaccination in Safety-Net Clinics: A Randomized Trial.
Trial report in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - BootCamp Translation
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Pilot Trial
PREVENT: Practice-based Approaches to Promote HPV Vaccination in the Safety Net - Randomized Controlled Trial (RCT)
Who cites it
25 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Estimating the effects of interventions on increasing vaccination: systematic review and meta-analysis.BMJ global health · 2025Pooled it
- A systematic review and meta-analysis of strategies to promote vaccination uptake.Nature human behaviour · 2024Pooled it
- Increasing HPV Vaccination Uptake among Adolescents: A Systematic Review.International journal of environmental research and public health · 2020Pooled it
- Patient reminder and recall interventions to improve immunization rates.The Cochrane database of systematic reviews · 2018Pooled it
- Targeting Vaccine Information Framing to Recipients' Education: A Randomized Trial.Health economics · 2025Trial
- Trial
- Improving childhood vaccination among minority populations in middle- and high-income countries: a realist review of health system interventions.Journal of epidemiology and community health · 2026Review
- Online Decision Support for Implementing Evidence-Based HPV Vaccination Strategies in Texas Safety-Net Pediatric Clinics: Impact on HPV, MCV, and Tdap Initiation.Healthcare (Basel, Switzerland) · 2026Article
- Education and social determinants shaping HPV vaccine uptake: Insights from a nationwide cross-sectional study.Human vaccines & immunotherapeutics · 2025Article
- Multilevel Interventions Aimed at Improving HPV Immunization Coverage: A Systematic Review and Meta-Analysis.Vaccines · 2025Review
- Development of an intervention to increase HPV vaccine uptake in Colombia.Pilot and feasibility studies · 2025Article
- Review
- Interventions employed to address vaccine hesitancy among Black populations outside of African and Caribbean countries: a scoping review.BMC public health · 2024Article
- EMR-Based Interventions on HPV Vaccination Initiation, Completion, and Receiving the Next Dose: A Meta-Analytic Review.Vaccines · 2024Review
- Building knowledge using a novel web-based intervention to promote HPV vaccination in a diverse, low-income population.Gynecologic oncology · 2024Article
- Systematic review and meta-analysis comparing educational and reminder digital interventions for promoting HPV vaccination uptake.NPJ digital medicine · 2023Article
- Factors associated with HPV vaccine acceptability and hesitancy among Black mothers with young daughters in the United States.Frontiers in public health · 2023Article
- Review
- "There's Always Next Year": Primary Care Team and Parent Perspectives on the Human Papillomavirus Vaccine.Human vaccines & immunotherapeutics · 2020Article
- Do traditional economic theories of free riding behavior explain spatial clustering of HPV vaccine uptake?SSM - population health · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
objectivesEvaluate effects of a multicomponent intervention (human papillomavirus [HPV] vaccine-specific brochure and recalls) on HPV vaccination and secondarily examine if race/ethnicity moderates effects.
methodsUnvaccinated girls aged 11 to 18 years attending 4 safety-net pediatric clinics and their parent/guardian (n = 814 dyads) were randomized to (1) active comparison (general adolescent vaccine brochure), or (2) intervention consisting of a HPV vaccine-specific brochure, telephone recalls to parents who declined, and recalls to patients overdue for doses 2 and 3. HPV 1-dose and 3-dose coverages were assessed via electronic health records 12 months after randomization. Multivariate logistic regressions estimated adjusted odds and marginal predicted vaccine coverage by study arm and race/ethnicity.
resultsIntent-to-treat analyses found no main effect of the HPV vaccine-specific brochure on 1-dose coverage (42.0% vs 40.6%); however, secondary analyses found race/ethnicity was a significant moderator such that the intervention was effective only for Hispanic individuals (adjusted odds ratio [AOR] 1.43; 95% confidence interval [CI] 1.02-2.02), and not effective for black individuals (AOR 0.64; 95% CI 0.41-1.13). Recalls to parents who declined the vaccine during the index visit were not effective, but recalls to patients overdue for doses 2 and 3 were effective at increasing 3-dose coverage regardless of race/ethnicity (AOR 1.99; 95% CI 1.16-3.45).
conclusionsEducational materials describing only the HPV vaccine were effective for Hispanic but not black individuals. Future research should test mechanisms that may mediate intervention effects for different racial/ethnic groups, such as different informational needs or vaccine schemas (experiences, beliefs, norms).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.