ArticlePediatrics2015
Psychosocial Adjustment in School-age Girls With a Family History of Breast Cancer.
Article in Pediatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 19 citations in OpenAlex.
- Steroids, stress, and body mass index interact to accelerate female pubertal development.The Journal of clinical endocrinology and metabolism · 2026Article
- A randomized study of digital versus genetic counselor return of actionable genetic research results to biobank participants (RESPECT3 study).BMC medical ethics · 2026Article
- An eHealth Delivery Alternative for Cancer Genetic Testing for Hereditary Predisposition in Patients With Metastatic Cancers: Protocol for a Randomized Trial.JMIR research protocols · 2025Article
- "I'm walking on eggshells": challenges faced by mothers with breast cancer in interacting with adolescent daughters.BMC women's health · 2022Article
- Balancing External Validity and Concern for Psychosocial Harms in Translational Genetic Research.Ethics & human research · 2021Article
- Prepubertal Internalizing Symptoms and Timing of Puberty Onset in Girls.American journal of epidemiology · 2021Article
- Self-care behaviors in high-risk women for breast cancer: A randomized clinical trial using health belief model education.Journal of education and health promotion · 2020Article
- Cancer genetic health communication in families tested for hereditary breast/ovarian cancer risk: a qualitative investigation of impact on children's genetic health literacy and psychosocial adjustment.Translational behavioral medicine · 2019Article
- Association of Prepubertal and Adolescent Androgen Concentrations With Timing of Breast Development and Family History of Breast Cancer.JAMA network open · 2019Article
- Preventative Health and Risk Behaviors Among Adolescent Girls With and Without Family Histories of Breast Cancer.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2019Article
- Please Test My Child for a Cancer Gene, but Don't Tell Her.Pediatrics · 2018Article
- The Precision Medicine Nation.The Hastings Center report · 2017Article
- Psychosocial Adjustment and Perceived Risk Among Adolescent Girls From Families With BRCA1/2 or Breast Cancer History.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2016Article
Corrections and comments
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Authors and funding
19 authors at 15 institutions in 4 countries.
Funding
Abstract
objectiveUnderstanding how young girls respond to growing up with breast cancer family histories is critical given expansion of genetic testing and breast cancer messaging. We examined the impact of breast cancer family history on psychosocial adjustment and health behaviors among >800 girls in the multicenter LEGACY Girls Study.
methodsGirls aged 6 to 13 years with a family history of breast cancer or familial BRCA1/2 mutation (BCFH+), peers without a family history (BCFH-), and their biological mothers completed assessments of psychosocial adjustment (maternal report for 6- to 13-year-olds, self-report for 10- to 13-year-olds), breast cancer-specific distress, perceived risk of breast cancer, and health behaviors (10- to 13-year-olds).
resultsBCFH+ girls had better general psychosocial adjustment than BCFH- peers by maternal report. Psychosocial adjustment and health behaviors did not differ significantly by self-report among 10- to 13-year-old girls. BCFH+ girls reported higher breast cancer-specific distress (P = .001) and were more likely to report themselves at increased breast cancer risk than BCFH- peers (38.4% vs 13.7%, P < .001), although many girls were unsure of their risk. In multivariable analyses, higher daughter anxiety was associated with higher maternal anxiety and poorer family communication. Higher daughter breast cancer-specific distress was associated with higher maternal breast cancer-specific distress.
conclusionsAlthough growing up in a family at risk for breast cancer does not negatively affect general psychosocial adjustment among preadolescent girls, those from breast cancer risk families experience greater breast cancer-specific distress. Interventions to address daughter and mother breast cancer concerns and responses to genetic or familial risk might improve psychosocial outcomes of teen daughters.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.