Trial reportPsychological medicine2016
Can community midwives prevent antenatal depression? An external pilot study to test the feasibility of a cluster randomized controlled universal prevention trial.
Trial report in Psychological medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Midwife continuity of care models versus other models of care for childbearing women.The Cochrane database of systematic reviews · 2024Pooled it
- Effectiveness of nurses and midwives-led psychological interventions on reducing depression symptoms in the perinatal period: A systematic review and meta-analysis.Nursing open · 2021Pooled it
- Non-pharmacological interventions to reduce the symptoms of mild to moderate anxiety in pregnant women. A systematic review and narrative synthesis of women's views on the acceptability of and satisfaction with interventions.Archives of women's mental health · 2020Pooled it
- Effectiveness of Psychological and Educational Interventions to Prevent Depression in Primary Care: A Systematic Review and Meta-Analysis.Annals of family medicine · 2017Pooled it
- Trial
- Article
- Adaptation and integration of the thinking healthy programme into pregnancy schools in Istanbul, Turkey.BMC pregnancy and childbirth · 2023Article
- The approach to managing perinatal anxiety: A mini-review.Frontiers in psychiatry · 2022Review
- Prevention of common mental disorders among women in the perinatal period: a critical mixed-methods review and meta-analysis.Global mental health (Cambridge, England) · 2022Review
- Facilitating Perinatal Access to Resources and Support (PeARS): a feasibility study with external pilot of a novel intervention.BMC pregnancy and childbirth · 2021Article
- Developing a complex intervention to support pregnant women with mild to moderate anxiety: application of the Medical Research Council framework.BMC pregnancy and childbirth · 2020Article
- Role of midwife-supported psychotherapy on antenatal depression, anxiety and maternal health: A meta-analysis and literature review.Experimental and therapeutic medicine · 2020Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRepeated epidemiological surveys show no decline in depression although uptake of treatments has grown. Universal depression prevention interventions are effective in schools but untested rigorously in adulthood. Selective prevention programmes have poor uptake. Universal interventions may be more acceptable during routine healthcare contacts for example antenatally. One study within routine postnatal healthcare suggested risk of postnatal depression could be reduced in non-depressed women from 11% to 8% by giving health visitors psychological intervention training. Feasibility and effectiveness in other settings, most notably antenatally, is unknown.
methodWe conducted an external pilot study using a cluster trial design consisting of recruitment and enhanced psychological training of randomly selected clusters of community midwives (CMWs), recruitment of pregnant women of all levels of risk of depression, collection of baseline and outcome data prior to childbirth, allowing time for women 'at increased risk' to complete CMW-provided psychological support sessions.
resultsSeventy-nine percent of eligible women approached agreed to take part. Two hundred and ninety-eight women in eight clusters participated and 186 termed 'at low risk' for depression, based on an Edinburgh Perinatal Depression Scale (EPDS) score of <12 at 12 weeks gestation, provided baseline and outcome data at 34 weeks gestation. All trial protocol procedures were shown to be feasible. Antenatal effect sizes in women 'at low risk' were similar to those previously demonstrated postnatally. Qualitative work confirmed the acceptability of the approach to CMWs and intervention group women.
conclusionA fully powered trial testing universal prevention of depression in pregnancy is feasible, acceptable and worth undertaking.
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