Evidence map›Paper›PMID 26482381›Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016

Effects of aerobic exercise on cancer-related fatigue: a meta-analysis of randomized controlled trials.

Li Tian, Hui J Lu, Lu Lin, Yan Hu

Abstract readComparative StudyMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 10 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 10 syntheses or guidelines pooled it, 118 citations in OpenAlex.

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  4. Effectiveness of exercise interventions in the management of cancer-related fatigue: a systematic review of systematic reviews.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  5. Risk factors for cancer-related fatigue in patients with colorectal cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
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  7. Music interventions can alleviate cancer-related fatigue: a metaanalysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  11. Exercise is more effective than health education in reducing fatigue in fatigued cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  12. Changes in Body Mass Index and Physical Activity Predict Changes in Vitality During a Weight Loss Trial in Breast Cancer Survivors.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Li TianSchool of Nursing, Fudan University, No. 305 Fenglin Road, Shanghai, 200032, China.
Hui J LuSchool of Nursing, Fudan University, No. 305 Fenglin Road, Shanghai, 200032, China.
Lu LinSchool of Nursing, Soochow University, Suzhou, China.
Yan HuSchool of Nursing, Fudan University, No. 305 Fenglin Road, Shanghai, 200032, China. huyan@fudan.edu.cn.
Fudan University · CNFirst Affiliated Hospital of Soochow University · CNSoochow University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer-related fatigue (CRF) is the most commonly reported and most distressing symptom in cancer patients. Currently, there are no effective strategies for managing this condition.

objectiveThe purpose of this study is to compare the effects of aerobic exercise on CRF with the standard of care.

methodsA systematic search for randomized controlled trials (RCTs) was performed using the Cochrane Library, JBI Library, Embase, MEDLINE, Web of Science, China Biology Medicine (CBM), and China National Knowledge Infrastructure (CNKI). The risk of bias was critically evaluated, and data were independently extracted by two reviewers. All of the analyses were performed using Review Manager 5.

resultsA total of 26 qualified studies that included 2830 participants (aerobic exercise, 1426; control, 1404) were included in the meta-analysis. Cancer patients who completed adjuvant therapy in the aerobic exercise group reported reduced CRF levels relative to patients undergoing the standard of care. Aerobic exercise had a moderate effect on CRF for patients not currently undergoing anticancer treatment. Supervised aerobic exercise, exercise for 20–30 min/session, or exercise three times/week had a small effect on CRF. Exercise for 50 min/session or exercise two sessions/week had a significant effect on patient CRF, whereas 8 weeks of exercise had a moderate effect.

conclusionsAerobic exercise is effective for the management of CRF, especially for patients who have completed adjuvant therapy. IMPLICATIONS FOR PRACTICE: Cancer patients can make more informed choices regarding their cancer-related fatigue management based on the best available evidence.

Indexed as

Exercise TherapyChinaExerciseFatigueHumansNeoplasmsRandomized Controlled Trials as Topic

Identifiers

PMID26482381
OpenAlexW2113716208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.