ArticleAntimicrobial agents and chemotherapy2016
Genomic Characteristics of NDM-Producing Enterobacteriaceae Isolates in Australia and Their blaNDM Genetic Contexts.
Article in Antimicrobial agents and chemotherapy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.
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50 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Prevalence of genes encoding carbapenem-resistance in Klebsiella pneumoniae recovered from clinical samples in Africa: systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Prevalence of carbapenemase-producing Enterobacteriaceae from human clinical samples in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2023Pooled it
- Transmission dynamics of ST346 carbapenem-resistantiScience · 2025Article
- Genomic and molecular characterization of a ceftazidime-avibactam resistant Klebsiella pneumoniae strain isolated from a Chinese tertiary hospital.BMC microbiology · 2025Article
- Predominance ofMedicina (Kaunas, Lithuania) · 2024Article
- Comparative Genomics of an Emerging Multidrug-ResistantAntibiotics (Basel, Switzerland) · 2024Article
- Detection of metallo-beta-lactamase-producing genesJournal of water and health · 2024Article
- Carbapenem resistance inAIMS microbiology · 2023Review
- Occurrence ofAntibiotics (Basel, Switzerland) · 2022Article
- NDM-5-ProducingAnimals : an open access journal from MDPI · 2022Article
- A Natural Novel Mutation in theMicrobiology spectrum · 2022Article
- Persistence and Dissemination Capacities of aAntibiotics (Basel, Switzerland) · 2022Article
- Carriage of distinct blaBMC genomics · 2022Article
- Molecular Epidemiology of New Delhi Metallo-Frontiers in microbiology · 2022Article
- Emergence of a NDM-1-producing ST25Frontiers in microbiology · 2022Article
- Article
- Characterization of beta-lactam-resistantMicrobial genomics · 2021Article
- Carbapenem-ResistantInfection and drug resistance · 2021Article
- Whole Genomic analysis of a clinical isolate of Uropathogenic Escherichia coli strain of Sequence Type - 101 carrying the drug resistance NDM-7 in IncX3 plasmid.Bioinformation · 2021Article
- Plasmid analysis of NDM metallo-β-lactamase-producing Enterobacterales isolated in Vietnam.PloS one · 2021Article
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6 authors.
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Abstract
blaNDM has been reported in different Enterobacteriaceae species and on numerous plasmid replicon types (Inc). Plasmid replicon typing, in combination with genomic characteristics of the bacterial host (e.g., sequence typing), is used to infer the spread of antimicrobial resistance determinants between genetically unrelated bacterial hosts. The genetic context of blaNDM is heterogeneous. In this study, we genomically characterized 12 NDM-producing Enterobacteriaceae isolated in Australia between 2012 and 2014: Escherichia coli (n = 6), Klebsiella pneumoniae (n = 3), Enterobacter cloacae (n = 2) and Providencia rettgeri (n = 1). We describe their blaNDM genetic contexts within Tn125, providing insights into the acquisition of blaNDM into Enterobacteriaceae. IncFII-type (n = 7) and IncX3 (n = 4) plasmids were the most common plasmid types found. The IncHI1B (n = 1) plasmid was also identified. Five different blaNDM genetic contexts were identified, indicating four particular plasmids with specific blaNDM genetic contexts (NGCs), three of which were IncFII plasmids (FII-A to -C). Of note, the blaNDM genetic context of P. rettgeri was not conjugative. Epidemiological links between our NDM-producing Enterobacteriaceae were established by their acquisition of these five particular plasmid types. The combination of different molecular and genetic characterization methods allowed us to provide insight into the spread of plasmids transmitting blaNDM.
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