ArticleJournal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation2016
Lean Body Mass and Survival in Hemodialysis Patients and the Roles of Race and Ethnicity.
Article in Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Circulating fatty acid profiles are associated with protein energy wasting in maintenance hemodialysis patients: a cross-sectional study.Scientific reports · 2021Trial
- Establishment of Prediction Equations of Lean Body Mass Suitable for Chinese Adults.BioMed research international · 2019Trial
- The Association of Social Determinants of Health on Mortality among Adults with End-Stage Kidney Disease: a Systematic Review and Meta-Analysis.Journal of racial and ethnic health disparities · 2026Review
- The association between body mass index and mortality in diabetic patients with end-stage renal disease is different in hemodialysis and peritoneal dialysis.Renal failure · 2025Article
- The role of lean body mass in predicting mortality in hemodialysis patients across different age groups.Scientific reports · 2025Article
- Physical Activity, Cardiorespiratory Fitness, and the Obesity Paradox with Consideration for Racial and/or Ethnic Differences: A Broad Review and Call to Action.Reviews in cardiovascular medicine · 2024Review
- Klotho and lean mass as novel cardiovascular risk factors in hemodialysis patients.Clinical kidney journal · 2023Article
- Obesity and chronic kidney disease: A current review.Obesity science & practice · 2023Review
- Clinical practice guideline exercise and lifestyle in chronic kidney disease.BMC nephrology · 2022Article
- Utilization of Mid-Thigh Magnetic Resonance Imaging to Predict Lean Body Mass and Knee Extensor Strength in Obese Adults.Frontiers in rehabilitation sciences · 2022Article
- αNutrients · 2021Article
- Predictive Value of Estimated Lean Body Mass for Neurological Outcomes after Out-of-Hospital Cardiac Arrest.Journal of clinical medicine · 2020Article
- Transfers to Hemodialysis Among US Patients Initiating Renal Replacement Therapy With Peritoneal Dialysis.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2019Article
- Severe muscle loss during radical chemoradiotherapy for non-metastatic nasopharyngeal carcinoma predicts poor survival.Cancer medicine · 2019Article
- Evaluation of body composition monitoring for assessment of nutritional status in hemodialysis patients.Renal failure · 2019Observational
- Observational
- Muscle mass assessment by computed tomography in chronic kidney disease patients: agreement with surrogate methods.European journal of clinical nutrition · 2019Article
- Comparison of Skinfold Thicknesses and Bioimpedance Spectroscopy to Dual-Energy X-Ray Absorptiometry for the Body Fat Measurement in Patients With Chronic Kidney Disease.Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition · 2017Article
- Characterization of Body Composition and Fat Mass Distribution 1 Year After Kidney Transplantation.Progress in transplantation (Aliso Viejo, Calif.) · 2017Article
- The Obesity Paradox in Kidney Disease: How to Reconcile it with Obesity Management.Kidney international reports · 2017Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundLean body mass (LBM) represents the "fat-free" muscle mass in hemodialysis (HD) patients and is an important nutritional measure. Previous studies have found that both higher LBM and body mass index (BMI) were related to greater survival in HD patients. Additional studies have shown differences in survival across racial-ethnic groups of HD patients. However, the association of LBM and mortality across racial-ethnic subgroups has not been examined.
objectiveWe hypothesize that racial differences in LBM affect the mortality in HD patients. SETTING AND SUBJECTS: Chronic HD patients from a large dialysis organization in the United States. PREDICTORS: Estimated LBM (eLBM), self-identified racial subgroups.
main outcome measure5-year survival. STUDY
designWe examined the association between baseline eLBM and survival using Cox proportional hazard models adjusted for demographics, comorbidities, and laboratory measures. Associations were examined across subgroups of race-ethnicity (non-Hispanic white, African American, and Hispanic) and BMI.
resultsThe final cohort included 117,683 HD patients, who were 62 ± 15 (mean ± standard deviation) years old, 43% women and 59% with diabetes mellitus. Higher eLBM was linearly associated with lower mortality. Compared with the reference group (48.4-<50.5 kg), patients with the lowest eLBM (<41.3 kg) had a 1.4-fold higher risk of mortality (hazard ratio: 1.37; 95% confidence interval: 1.30-1.44) in the fully adjusted model. A similar linear association was seen among patients with BMI < 35 kg/m(2) and in non-Hispanic whites and African American subgroups. However, higher eLBM was not associated with improved survival in Hispanic patients or patients with BMI ≥ 35 kg/m(2). LIMITATION: Potential residual confounding.
conclusionsHigher eLBM is associated with a lower mortality risk in HD patients, especially among non-Hispanic white and African American groups. Hispanic patients do not demonstrate a similar inverse relationship. The association between LBM and mortality among different racial groups of HD patients deserves additional study.
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