Evidence map›Paper›PMID 26482028›Full record

ArticleBMC geriatrics2015

A retrospective, longitudinal study of factors associated with new antipsychotic medication use among recently admitted long-term care residents.

Andrea Foebel, Anna Ballokova, Nathalie I H Wellens, Daniela Fialova, Koen Milisen, Rosa Liperoti, John P Hirdes

Abstract read
In one paragraph

Article in BMC geriatrics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea FoebelDepartment of Medical Epidemiology and Biostatistics Karolinska Institutet, Nobels väg 12A, Stockholm, Sweden. andrea.foebel@ki.se.
Anna BallokovaDepartment of Geriatrics and Gerontology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic. anna.ballokova@seznam.cz.
Nathalie I H WellensDepartment of Public Health and Primary Care, Center for Health Services and Nursing Research, KULeuven, Leuven, Belgium. Nathalie.Wellens@med.kuleuven.be.
Daniela FialovaDepartment of Geriatrics and Gerontology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic. Daniela.Fialova@lf1.cuni.cz.
Koen MilisenDepartment of Public Health and Primary Care, Center for Health Services and Nursing Research, KULeuven, Leuven, Belgium. Koen.Milisen@med.kuleuven.be.
Rosa LiperotiCentro Medicina dell'Invecchiamento, Università Cattolica del Sacro Cuore, Rome, Italy. rosella.liperoti@rm.unicatt.it.
John P HirdesSchool of Public Health and Health Systems, University of Waterloo, Waterloo, Canada. hirdes@uwaterloo.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUse of antipsychotic (AP) medications is high and often inappropriate among institutionalized populations. Little is known about the correlates of new AP drug use following admission to long-term care (LTC) settings. This study investigated the frequency and correlates of new AP drug use among newly admitted LTC residents.

methodsThis longitudinal, retrospective study used data from the interRAI - Nursing Home Minimum Data Set version 2.0 (MDS 2.0) instrument. Data about demographic, clinical and social characteristics, and medication use, were collected in Ontario, Canada, from 2003-2011 by trained nurses. Residents with complete admission and 3-6 month follow-up data were included (N = 47,768). Multivariate logistic regression analyses, stratified by gender, explored correlates of new AP drug use upon admission to LTC.

resultsNew AP drug users comprised 7 % of the final cohort. Severe cognitive impairment, dementia, and motor agitation were significantly associated with new AP drug use among both sexes. Additionally, behavioural problems, conflicts with staff and reduced social engagement were strong correlates of new AP drug use.

conclusionsSocial factors were as strongly associated with new AP drug use after LTC admission as clinical factors. Strategies to prevent the potential misuse of AP drugs upon LTC admission should consider the social determinants of such prescribing.

Indexed as

AgedAntipsychotic AgentsDementiaFemaleFollow-Up StudiesHumansLongitudinal StudiesLong-Term CareMaleNursing HomesOntarioPatient AdmissionPsychomotor AgitationRetrospective StudiesAntipsychotic Agents

Identifiers

PMID26482028
PMCPMC4615888

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.