Evidence map›Paper›PMID 26481915›Full record

Trial reportClinical research in cardiology : official journal of the German Cardiac Society2016

Heart-focused anxiety in patients with chronic heart failure before implantation of an implantable cardioverter defibrillator: baseline findings of the Anxiety-CHF Study.

Maxie Bunz, Denise Lenski, Sonja Wedegärtner, Christian Ukena, Julia Karbach, Michael Böhm, Ingrid Kindermann

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Clinical research in cardiology : official journal of the German Cardiac Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02226770 (Heart-focused Anxiety in Patients With Implantable Cardioverter Defibrillator), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02226770 nacompletednot on this map

Heart-focused Anxiety in Patients With Implantable Cardioverter Defibrillator (ICD) and/or Mechanical Cardiovascular Assist Device (AD) (Anxiety-CHF)

TypeinterventionalSponsorUniversity Hospital, SaarlandRan2010 to 2016Enrolled132ConditionsHeart Failure Patients Before and After ICD ImplantationArmsImplantable Cardioverter Defibrillator (ICD)
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Functional status and quality of life after transcatheter mitral valve repair: a prospective cohort study and systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Prognostic impact of recurrences of ventricular tachyarrhythmias and appropriate ICD therapies in a high-risk ICD population.Clinical research in cardiology : official journal of the German Cardiac Society · 2019
    Article
  8. Article
  9. Article
  10. Stratified prevention: opportunities and limitations. Report on the 1st interdisciplinary cardiovascular workshop in Augsburg.Clinical research in cardiology : official journal of the German Cardiac Society · 2018
    Review
  11. Article
  12. Posttraumatic stress and quality of life with the totally subcutaneous compared to conventional cardioverter-defibrillator systems.Clinical research in cardiology : official journal of the German Cardiac Society · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maxie BunzKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany. Maxie.Bunz@uks.eu.
Denise LenskiKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Sonja WedegärtnerKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Christian UkenaKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Julia KarbachInstitut für Psychologie, Goethe-Universität, Frankfurt, Germany.
Michael BöhmKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany.
Ingrid KindermannKlinik für Innere Medizin III-Kardiologie, Angiologie und Intensivmedizin, Universitätsklinikum des Saarlandes, Homburg/Saar, Germany. ingrid.kindermann@uks.eu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe analysed heart-focused anxiety (HFA) and its predictors in patients with heart failure before implantation of an implantable cardioverter defibrillator (ICD). Herein, we report the baseline data of the Anxiety-CHF Study which investigates HFA before and after ICD implantation. METHODS AND

resultsHFA, general anxiety and depression, perceived quality of life (QoL) and type D personality were measured with validated psychological instruments. Clinical parameters such as severity of heart failure measured by NYHA class and left ventricular ejection fraction (EF) were determined. One hundred and ten patients were interrogated before ICD implantation (70 % male, mean age = 60.5 ± 14.9 years, mean EF = 31 % ± 9 %, 91 % NYHA II-III, 92 % primary prevention). HFA was present in 53 patients (48.6 %); 37 participants (33.9 %) showed increased levels of general anxiety and 33 patients (30.3 %) showed increased levels of depression with clinical significant levels in 16 subjects (14.7 %) for general anxiety and 13 subjects (11.9 %) for depression. Poor QoL was reported in 30 patients (27.5 %). HFA was correlated with QoL, general anxiety, depression, type D personality, myocardial infarction (MI), and systolic blood pressure. QoL, general anxiety and former MI were significant predictors of HFA (R (2) = 0.453).

conclusionHeart-focused anxiety is highly prevalent in heart failure patients prior to ICD implantation. Measures of disease severity such as EF or NYHA class do not predict HFA, neither does Type D personality. HFA is predicted by a history of MI and psychological parameters such as general anxiety and impaired QoL. CLINICALTRIALS. GOV IDENTIFIER: NCT02226770.

Indexed as

AgedAnxietyChronic DiseaseComorbidityCost of IllnessCross-Sectional StudiesDefibrillators, ImplantableElectric CountershockFemaleGermanyHeart FailureHumansIncidenceMaleMiddle AgedPrevalenceCRT-DHeart-focused anxietyICDPsychological factorsQuality of lifeType D personality

Identifiers

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.