ArticleBMC genomics2015
De novo transcriptome analysis of Medicago falcata reveals novel insights about the mechanisms underlying abiotic stress-responsive pathway.
Article in BMC genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Comparative transcriptome analysis of differentially expressed genes of Medicago falcata L. breeding lines response to saline-alkaline stress.BMC plant biology · 2025Article
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- De Novo Transcriptome Assembly of Rice Bean (Plants (Basel, Switzerland) · 2024Article
- Transcriptional Profiling Analysis Providing Insights into the Harsh Environments Tolerance Mechanisms ofInternational journal of molecular sciences · 2024Article
- Integrated Metabolomic and Transcriptomic Profiles Provide Insights into the Mechanisms of Anthocyanin and Carotenoid Biosynthesis in Petals ofPlants (Basel, Switzerland) · 2024Article
- Variability of plant transcriptomic responses under stress acclimation: a review from high throughput studies.Acta biochimica Polonica · 2024Review
- Integrated Transcriptomic and Metabolomic Analyses of Cold-Tolerant and Cold-Sensitive Pepper Species Reveal Key Genes and Essential Metabolic Pathways Involved in Response to Cold Stress.International journal of molecular sciences · 2022Article
- Transcriptome and functional analyses revealFrontiers in plant science · 2022Article
- Low Temperature Stress Tolerance: An Insight Into the Omics Approaches for Legume Crops.Frontiers in plant science · 2022Review
- Physiological and transcriptome analyses highlight multiple pathways involved in drought stress in Medicago falcata.PloS one · 2022Article
- Strategies to Apply Water-Deficit Stress: Similarities and Disparities at the Whole Plant Metabolism Level inInternational journal of molecular sciences · 2021Article
- In silico mining and functional analysis of AP2/ERF gene in Withania somnifera.Scientific reports · 2020Article
- Article
- Integrated transcriptomic and metabolomic analyses of yellow horn (Xanthoceras sorbifolia) in response to cold stress.PloS one · 2020Article
- Gene Regulatory Network Guided Investigations and Engineering of Storage Root Development in Root Crops.Frontiers in plant science · 2020Review
- Full-length transcriptome sequencing reveals the low-temperature-tolerance mechanism of Medicago falcata roots.BMC plant biology · 2019Article
- Identification of Genes Differentially Expressed in Response to Cold inPlants (Basel, Switzerland) · 2019Article
- Medicago falcata MfSTMIR, an E3 ligase of endoplasmic reticulum-associated degradation, is involved in salt stress response.The Plant journal : for cell and molecular biology · 2019Article
- Comparative Transcriptomic and Physiological Analyses ofInternational journal of molecular sciences · 2018Article
- Article
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Authors and funding
15 authors.
Funding
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Abstract
backgroundThe entire world is facing a deteriorating environment. Understanding the mechanisms underlying plant responses to external abiotic stresses is important for breeding stress-tolerant crops and herbages. Phytohormones play critical regulatory roles in plants in the response to external and internal cues to regulate growth and development. Medicago falcata is one of the stress-tolerant candidate leguminous species and is able to fix atmospheric nitrogen. This ability allows leguminous plants to grow in nitrogen deficient soils.
methodsWe performed Illumina sequencing of cDNA prepared from abiotic stress treated M. falcata. Sequencedreads were assembled to provide a transcriptome resource. Transcripts were annotated using BLASTsearches against the NCBI non-redundant database and gene ontology definitions were assigned. Acomparison among the three abiotic stress treated samples was carried out. The expression of transcriptswas confirmed with qRT-PCR.
resultsWe present an abiotic stress-responsive M. falcata transcriptome using next-generation sequencing data from samples grown under standard, dehydration, high salinity, and cold conditions. We combined reads from all samples and de novo assembled 98,515 transcripts to build the M. falcata gene index. A comprehensive analysis of the transcriptome revealed abiotic stress-responsive mechanisms underlying the metabolism and core signalling components of major phytohormones. We identified nod factor signalling pathways during early symbiotic nodulation that are modified by abiotic stresses. Additionally, a global comparison of homology between the M. falcata and M. truncatula transcriptomes, along with five other leguminous species, revealed a high level of global sequence conservation within the family.
conclusionsM. falcata is shown to be a model candidate for studying abiotic stress-responsive mechanisms in legumes. This global gene expression analysis provides new insights into the biochemical and molecular mechanisms involved in the acclimation to abiotic stresses. Our data provides many gene candidates that might be used for herbage and crop breeding. Additionally, FalcataBase ( http://bioinformatics.cau.edu.cn/falcata/ ) was built for storing these data.
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