ArticleApplied optics2015
Alignment of sources and detectors on breast surface for noncontact diffuse correlation tomography of breast tumors.
Article in Applied optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Diffuse correlation tomography: a technique to characterize tissue blood flow abnormalities in benign and malignant breast lesions.Biomedical optics express · 2024Article
- Detection of low-frequency oscillations in neonatal piglets with speckle contrast diffuse correlation tomography.Journal of biomedical optics · 2023Article
- Depth-sensitive diffuse speckle contrast topography for high-density mapping of cerebral blood flow in rodents.Neurophotonics · 2023Article
- A Wearable Fiber-Free Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Freely Behaving Mice.IEEE transactions on bio-medical engineering · 2023Article
- High-density diffuse correlation tomography with enhanced depth localization and minimal surface artefacts.Biomedical optics express · 2022Article
- Speckle contrast diffuse correlation tomography of cerebral blood flow in perinatal disease model of neonatal piglets.Journal of biophotonics · 2021Article
- Simultaneous measurements of tissue blood flow and oxygenation using a wearable fiber-free optical sensor.Journal of biomedical optics · 2021Article
- Noncontact optical imaging of brain hemodynamics in preterm infants: a preliminary study.Physics in medicine and biology · 2020Article
- Noninvasive noncontact speckle contrast diffuse correlation tomography of cerebral blood flow in rats.NeuroImage · 2019Article
- Noncontact speckle contrast diffuse correlation tomography of blood flow distributions in tissues with arbitrary geometries.Journal of biomedical optics · 2018Article
- Noncontact 3-D Speckle Contrast Diffuse Correlation Tomography of Tissue Blood Flow Distribution.IEEE transactions on medical imaging · 2017Article
- Clinical applications of near-infrared diffuse correlation spectroscopy and tomography for tissue blood flow monitoring and imaging.Physiological measurement · 2017Review
- Heterodyne frequency-domain multispectral diffuse optical tomography of breast cancer in the parallel-plane transmission geometry.Medical physics · 2016Article
- Scanning, non-contact, hybrid broadband diffuse optical spectroscopy and diffuse correlation spectroscopy system.Biomedical optics express · 2016Article
- A Wearable Fiberless Optical Sensor for Continuous Monitoring of Cerebral Blood Flow in Mice.IEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics SocietyArticle
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Noncontact diffuse correlation tomography (ncDCT) is an emerging technology for 3D imaging of deep tissue blood flow distribution without distorting hemodynamic properties. To adapt the ncDCT for imaging in vivo breast tumors, we designed a motorized ncDCT probe to scan over the breast surface. A computer-aided design (CAD)-based approach was proposed to create solid volume mesh from arbitrary breast surface obtained by a commercial 3D camera. The sources and detectors of ncDCT were aligned on the breast surface through ray tracing to mimic the ncDCT scanning with CAD software. The generated breast volume mesh along with the boundary data of ncDCT at the aligned source and detector pairs were used for finite-element-method-based flow image reconstruction. We evaluated the accuracy of source alignments on mannequin and human breasts; largest alignment errors were less than 10% in both tangential and radial directions of scanning. The impact of alignment errors (assigned 10%) on the tumor reconstruction was estimated using computer simulations. The deviations of simulated tumor location and blood flow contrast resulted from the alignment errors were 0.77 mm (less than the node distance of 1 mm) and 1%, respectively, which result in minor impact on flow image reconstruction. Finally, a case study on a human breast tumor was conducted and a tumor-to-normal flow contrast was reconstructed, demonstrating the feasibility of ncDCT in clinical application.
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