ArticlePloS one2015
Sensitivity of Hyperdense Basilar Artery Sign on Non-Enhanced Computed Tomography.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 13 citations in OpenAlex.
- Current state and advancements of imaging in acute ischemic stroke: a practical review.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Review
- Early Detection of Hyperdense Basilar Artery Signs Through Comparison With Previous Images.Cureus · 2024Article
- Radiology resident competency in detecting basilar artery occlusion: a simulation-based assessment.Emergency radiology · 2024Article
- Diagnostic and prognostic computed tomography imaging markers in basilar artery occlusion (Review).Experimental and therapeutic medicine · 2021Review
- Assessment of Vessel Density on Non-Contrast Computed Tomography to Detect Basilar Artery Occlusion.The western journal of emergency medicine · 2020Article
- Basilar Artery Occlusion: Diagnosis and Acute Treatment.Current treatment options in neurology · 2019Review
- Brain computerized tomography reading in suspected acute ischemic stroke patients: what are essentials for medical students?BMC medical education · 2019Article
- "Hyperdense artery sign" in early ischemic stroke: diagnostic value of model-based reconstruction approach in comparison with standard hybrid iterative reconstruction algorithm.Neuroradiology · 2018Observational
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe hyperdense basilar artery sign (HBAS) is an indicator of vessel occlusion on non contrast-enhanced computer tomography (NECT) in acute stroke patients. Since basilar artery occlusion (BAO) is associated with a high mortality and morbidity, its early detection is of great clinical value. We sought to analyze the influence of density measurement as well as a normalized ratio of Hounsfield unit/hematocrit (HU/Hct) ratio on the detection of BAO on NECT in patients with suspected BAO. MATERIALS AND
methods102 patients with clinically suspected BAO were examined with NECT followed immediately by Multidetector computed tomography Angiography. Two observers independently analyzed the images regarding the presence or absence of HBAS on NECT and performed HU measurements in the basilar artery. Receiver operating characteristic curve analysis was performed to determine the optimal density threshold for BAO using attenuation measurements or HU/Hct ratio.
resultsSensitivity of visual detection of the HBAS on NECT was relatively low 81% (95%-CI, 54-95%) while specificity was high 91% (95%-CI, 82-96%). The highest sensitivity was achieved by the combination of visual assessment and additional quantitative attenuation measurements applying a cut-off value of 46.5 HU with 94% sensitivity and 81% specificity for BAO. A HU/Hct ratio >1.32 revealed sensitivity of 88% (95%-CI, 60-98%) and specificity of 84% (95%-CI, 74-90%).
conclusionIn patients with clinically suspected acute BAO the combination of visual assessment and additional attenuation measurement with a cut-off value of 46.5 HU is a reliable approach with high sensitivity in the detection of BAO on NECT.
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