Evidence map›Paper›PMID 26478511›Full record

ArticlePublic health action2014

Adherence to anti-tuberculosis treatment in Tigray, Northern Ethiopia.

Y K Kiros, T Teklu, F Desalegn, M Tesfay, E Klinkenberg, A Mulugeta

Open access · diamondAbstract read
In one paragraph

Article in Public health action, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
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  6. Article
  7. Factors Associated with Medication Adherence in Elderly Individuals with Tuberculosis: A Qualitative Study.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Nonadherence Predictors to Tuberculosis Medications among TB Patients in Gambella Region of Ethiopia.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2022
    Article
  12. Article
  13. Article
  14. Factors Influencing Patient Adherence to Tuberculosis Treatment in Ethiopia: A Literature Review.International journal of environmental research and public health · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Y K KirosMekelle University, Mekelle, Ethiopia.
T TekluTigray Regional Health Bureau, Mekelle, Ethiopia.
F DesalegnMekelle Hospital, Mekelle, Ethiopia.
M TesfayTigray Regional Laboratory, Mekelle, Ethiopia.
E KlinkenbergKNCV Tuberculosis Foundation, The Hague, The Netherlands ; Department of Global Health, Academic Medical Centre, University of Amsterdam, Amsterdam Institute for Global Health and Development, Amsterdam, The Netherlands.
A MulugetaMekelle University, Mekelle, Ethiopia.
Mekelle University · ETAmsterdam Institute for Global Health and Development · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

settingTuberculosis (TB) patients in Mekelle Zone, Tigray Region, in Ethiopia.

objectiveTo investigate adherence to anti-tuberculosis treatment.

designA cross-sectional study in health facilities providing anti-tuberculosis treatment was conducted. Adherence was measured in three ways: through self-reported missed doses, by visual analogue scale whereby patients rate their own adherence and by record review. A patient was considered to be adherent if 90% or more of the prescribed medication was taken.

resultOf 278 TB patients included, 101 were in the intensive and 177 in the continuation phase. Respectively 67 (24.1%), 130 (46.8%) and 80 (28.8%) patients had smear-positive, smear-negative and extra-pulmonary TB. Self-report of missed doses and record review indicated adherence of respectively 273 (97.3%) and 271 (97.5%) patients. By visual analogue scale, 250 (91.6%) patients rated themselves as adherent. History of drug side effects (aOR 0.25, 95%CI 0.08-0.77) and knowledge about TB prevention (aOR 0.19, 95%CI 0.05-0.8) were independently associated with being adherent in this setting.

conclusionAdherence to anti-tuberculosis treatment was high in our study. Adherence support should be given to the poor, the elderly, patients co-infected with the human immunodeficiency virus, alcohol abusers and smokers. Health education on TB prevention should be given to all TB patients regularly.

Indexed as

continuation phaseintensive phaserecord reviewrisk factorvisual analogue scale

Identifiers

PMID26478511
PMCPMC4542072
OpenAlexW2002306802

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.