ReviewCurrent psychiatry reports2015
Genetic Similarities between Compulsive Overeating and Addiction Phenotypes: A Case for "Food Addiction"?
Review in Current psychiatry reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Genetic susceptibility to caffeine intake and metabolism: a systematic review.Journal of translational medicine · 2024Pooled it
- How Does the Ultra-Processed Food Industry Drive Consumption Through Product Design and Marketing? Mapping a Complex Commercial System According to Expert Mental Models and Evidence Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Shared and Unique Risk Factors for Binge Eating and Binge Drinking in a Community-based Sample of Girls.Research on child and adolescent psychopathology · 2025Article
- Food Addiction: Prevalence, Severity, and Impact on Vascular Stroke Risk Factors in a French Hospital-Based Sample.Nutrients · 2024Article
- Psychosocial risk and protective factors for youth problem behavior are associated with food addiction in the Generation Z.Frontiers in public health · 2024Article
- Prevalence of food addiction using the Yale-C scale in Mexican children with overweight and obesity.PeerJ · 2022Article
- Sleep dysregulation in binge eating disorder and "food addiction": the orexin (hypocretin) system as a potential neurobiological link.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Review
- Obesity as a Condition Determined by Food Addiction: Should Brain Endocannabinoid System Alterations Be the Cause and Its Modulation the Solution?Pharmaceuticals (Basel, Switzerland) · 2021Review
- Validation of the Turkish version of the power of food scale in adult population.Eating and weight disorders : EWD · 2021Article
- 'Liking' and 'wanting' in eating and food reward: Brain mechanisms and clinical implications.Physiology & behavior · 2020Review
- Prisoners of Addictive Cues: Biobehavioral Markers of Overweight and Obese Adults with Food Addiction.Nutrients · 2020Article
- Impact of High Fat Diet and Ethanol Consumption on Neurocircuitry Regulating Emotional Processing and Metabolic Function.Frontiers in behavioral neuroscience · 2020Review
- Eating Behavior, Stress, and Adiposity: Discordance Between Perception and Physiology.Biological research for nursing · 2018Article
- Decision Making Deficits in Relation to Food Cues Influence Obesity: A Triadic Neural Model of Problematic Eating.Frontiers in psychiatry · 2018Article
- Eating disorders and food addiction in men with heroin use disorder: a controlled study.Eating and weight disorders : EWD · 2017Article
- Cytoplasmic FMR1-Interacting Protein 2 Is a Major Genetic Factor Underlying Binge Eating.Biological psychiatry · 2017Article
- Wistar-Kyoto Female Rats Are More Susceptible to Develop Sugar Binging: A Comparison with Wistar Rats.Frontiers in nutrition · 2017Article
- Palatable Hyper-Caloric Foods Impact on Neuronal Plasticity.Frontiers in behavioral neuroscience · 2017Review
- Genetic epidemiology of eating disorders.Current opinion in psychiatry · 2016Review
- A genome-wide investigation of food addiction.Obesity (Silver Spring, Md.) · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There exists a continuous spectrum of overeating, where at the extremes there are casual overindulgences and at the other a 'pathological' drive to consume palatable foods. It has been proposed that pathological eating behaviors may be the result of addictive appetitive behavior and loss of ability to regulate the consumption of highly processed foods containing refined carbohydrates, fats, salt, and caffeine. In this review, we highlight the genetic similarities underlying substance addiction phenotypes and overeating compulsions seen in individuals with binge eating disorder. We relate these similarities to findings from neuroimaging studies on reward processing and clinical diagnostic criteria based on addiction phenotypes. The abundance of similarities between compulsive overeating and substance addictions puts forth a case for a 'food addiction' phenotype as a valid, diagnosable disorder.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.