Evidence map›Paper›PMID 26477743›Full record

ReviewTrends in genetics : TIG2015

Drosophila Chemoreceptors: A Molecular Interface Between the Chemical World and the Brain.

Ryan M Joseph, John R Carlson

Abstract readReview
In one paragraph

Review in Trends in genetics : TIG, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 188 papers.

0numbers the graph read from it
0cells of the map it votes in
188citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

188 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecular bases of insect odorant receptor function: specificity and evolution.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  8. Receptor sequence divergence, gain, loss, duplication, and neofunctionalization drive olfactory adaptation inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  9. Gustatory sensing by ovipositor drives maternal avoidance of hesperidin to benefit the offspring in a major agricultural fly pest.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Genomic plasticity drives olfactory adaptation in a pest fly.bioRxiv : the preprint server for biology · 2025
    Article
  18. Article
  19. Review
  20. Article

128 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ryan M JosephDepartment of Molecular, Cellular, and Developmental Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103, USA.
John R CarlsonDepartment of Molecular, Cellular, and Developmental Biology, Yale University, PO Box 208103, New Haven, CT 06520-8103, USA. Electronic address: john.carlson@yale.edu.

Funding

ANALYSIS OF ODORANT RECEPTOR GENESR01DC004729 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2001 to 2026
$9.2M
GENETIC AND MOLECULAR ANALYSIS OF OLFACTIONR01DC002174 · NIDCD · YALE UNIVERSITY · PI CARLSON, JOHN R · 1994 to 2024
$8.0M
Analysis of a large family of taste receptorsR01DC011697 · NIDCD · YALE UNIVERSITY · PI John R Carlson · 2011 to 2026
$5.5M
NIDCD NIH HHS R01 DC002174NIDCD NIH HHS R01 DC004729NIDCD NIH HHS R01 DC011697
6 · The paper itself

Abstract

Chemoreception is essential for survival. Feeding, mating, and avoidance of predators depend on detection of sensory cues. Drosophila contains diverse families of chemoreceptors that detect odors, tastants, pheromones, and noxious stimuli, including receptors of the odor receptor (Or), gustatory receptor (Gr), ionotropic receptor (IR), Pickpocket (Ppk), and Trp families. We consider recent progress in understanding chemoreception in the fly, including the identification of new receptors, the discovery of novel biological functions for receptors, and the localization of receptors in unexpected places. We discuss major unsolved problems and suggest areas that may be particularly ripe for future discoveries, including the roles of these receptors in driving the circuits and behaviors that are essential to the survival and reproduction of the animal.

Indexed as

AnimalsBrainDrosophila melanogasterReceptors, Cell SurfaceSmellTasteReceptors, Cell Surfacegustatory receptorionotropic glutamate receptorodor receptorolfactionolfactory receptor neurontaste

Identifiers

PMID26477743
PMCPMC4674303

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.