Evidence map›Paper›PMID 26477609›Full record

ReviewThe Prostate2016

Multidisciplinary intervention of early, lethal metastatic prostate cancer: Report from the 2015 Coffey-Holden Prostate Cancer Academy Meeting.

Andrea K Miyahira, Joshua M Lang, Robert B Den, Isla P Garraway, Tamara L Lotan, Ashley E Ross, Tanya Stoyanova, Steve Y Cho, Jonathan W Simons, Kenneth J Pienta and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in The Prostate, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

  1. C-reactive protein-albumin-lymphocyte index predicts biochemical recurrence in prostate cancer.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Andrea K MiyahiraProstate Cancer Foundation, Santa Monica, California.
Joshua M LangUniversity of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin.
Robert B DenDepartment of Radiation Oncology, Sidney Kimmel Medical Center, Thomas Jefferson University, Philadelphia, Pennsylvania.
Isla P GarrawayDepartment of Urology, David Geffen School of Medicine at UCLA, Los Angeles, California.
Tamara L LotanDepartment of Pathology, The Johns Hopkins School of Medicine, Baltimore, Maryland.
Ashley E RossDepartment of Pathology, The Johns Hopkins School of Medicine, Baltimore, Maryland.
Tanya StoyanovaDepartment of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California.
Steve Y ChoUniversity of Wisconsin Carbone Comprehensive Cancer Center, Madison, Wisconsin.
Jonathan W SimonsProstate Cancer Foundation, Santa Monica, California.
Kenneth J PientaDepartment of Oncology, The Johns Hopkins School of Medicine, Baltimore, Maryland.
Howard R SouleProstate Cancer Foundation, Santa Monica, California.
Johns Hopkins University · USProstate Cancer Foundation · USUniversity of California, Los Angeles · USUniversity of Wisconsin–Madison · USThomas Jefferson University · US

Funding

Prostate Cancer Bone Metastasis: Biology and TargetingP01CA098912 · NCI · EMORY UNIVERSITY · PI CHUNG, LELAND W.K. · 2003 to 2019
$24.0M
NCI NIH HHS P01 CA098912
6 · The paper itself

Abstract

backgroundThe 2015 Coffey-Holden Prostate Cancer Academy Meeting, themed: "Multidisciplinary Intervention of Early, Lethal Metastatic Prostate Cancer," was held in La Jolla, California from June 25 to 28, 2015.

methodsThe Prostate Cancer Foundation (PCF) sponsors an annual, invitation-only, action-tank-structured meeting on a critical topic concerning lethal prostate cancer. The 2015 meeting was attended by 71 basic, translational, and clinical investigators who discussed the current state of the field, major unmet needs, and ideas for addressing earlier diagnosis and treatment of men with lethal prostate cancer for the purpose of extending lives and making progress toward a cure.

resultsThe questions addressed at the meeting included: cellular and molecular mechanisms of tumorigenesis, evaluating, and targeting the microenvironment in the primary tumor, advancing biomarkers for clinical integration, new molecular imaging technologies, clinical trials, and clinical trial design in localized high-risk and oligometastatic settings, targeting the primary tumor in advanced disease, and instituting multi-modal care of high risk and oligometastatic patients. DISCUSSION: This article highlights the current status, greatest unmet needs, and anticipated field changes that were discussed at the meeting toward the goal of optimizing earlier interventions to potentiate cures in high-risk and oligometastatic prostate cancer patients.

Indexed as

Academies and InstitutesCongresses as TopicPatient Care TeamResearch ReportCaliforniaEarly Medical InterventionHumansInterprofessional RelationsMaleProstatic Neoplasmsbiomarkersdiagnosismolecular imagingoligometastatictherapeutics

Identifiers

PMID26477609
PMCPMC5830186
OpenAlexW2146875652

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.