ArticleMagnetic resonance imaging2016
Visualizing functional pathways in the human brain using correlation tensors and magnetic resonance imaging.
Article in Magnetic resonance imaging, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed.
- Disrupted white matter functional connectivity in post-stroke cognitive impairment: Insights from resting-state fMRI.Brain imaging and behavior · 2026Article
- Developmental changes of the white matter functional connectome.Molecular psychiatry · 2026Article
- White matter structure-function coupling in neonatal brain and its association with Autism-related traits in early childhood.Translational psychiatry · 2026Article
- Robust Containerization of the High Angular Resolution Functional Imaging (HARFI) Pipeline.Neuroinformatics · 2026Article
- Altered Topological Properties of White-Matter Functional Networks in Young Smokers.Addiction biology · 2026Article
- White matter structure-function coupling alteration is associated with plasma biomarkers and cognition in Alzheimer's disease.European radiology · 2025Article
- Beyond tractography in brain connectivity mapping with dMRI morphometry and functional networks.Brain structure & function · 2025Review
- Multi-Metric Approach for the Comparison of Denoising Techniques for Resting-State fMRI.Human brain mapping · 2025Article
- Vasculature-informed spatial smoothing of white matter functional magnetic resonance imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- A 4D atlas of diffusion-informed spatial smoothing windows for BOLD signal in white matter.Proceedings of SPIE--the International Society for Optical Engineering · 2025Article
- WhiFuN: A toolbox to map the white matter functional networks of the human brain.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Functional connectivity between the uncinate fasciculus and frontotemporal semantic system supports reading comprehension in adolescents.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Structure-function coupling in white matter uncovers the hypoconnectivity in autism spectrum disorder.Molecular autism · 2024Article
- Functional correlation tensors in brain white matter and the effects of normal aging.Brain imaging and behavior · 2024Article
- Abnormal multimodal neuroimaging patterns associated with social deficits in male autism spectrum disorder.Human brain mapping · 2024Article
- Sub-bundle based analysis reveals the role of human optic radiation in visual working memory.Human brain mapping · 2024Article
- Article
- Characteristic BOLD signals are detectable in white matter of the spinal cord at rest and after a stimulus.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Neuropathological characteristics of abnormal white matter functional signaling in adolescents with major depression.World journal of psychiatry · 2024Article
- The missing third dimension-Functional correlations of BOLD signals incorporating white matter.Science advances · 2024Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
Functional magnetic resonance imaging usually detects changes in blood oxygenation level dependent (BOLD) signals from T2*-sensitive acquisitions, and is most effective in detecting activity in brain cortex which is irrigated by rich vasculature to meet high metabolic demands. We recently demonstrated that MRI signals from T2*-sensitive acquisitions in a resting state exhibit structure-specific temporal correlations along white matter tracts. In this report we validate our preliminary findings and introduce spatio-temporal functional correlation tensors to characterize the directional preferences of temporal correlations in MRI signals acquired at rest. The results bear a remarkable similarity to data obtained by diffusion tensor imaging but without any diffusion-encoding gradients. Just as in gray matter, temporal correlations in resting state signals may reflect intrinsic synchronizations of neural activity in white matter. Here we demonstrate that functional correlation tensors are able to visualize long range white matter tracts as well as short range sub-cortical fibers imaged at rest, and that evoked functional activities alter these structures and enhance the visualization of relevant neural circuitry. Furthermore, we explore the biophysical mechanisms underlying these phenomena by comparing pulse sequences, which suggest that white matter signal variations are consistent with hemodynamic (BOLD) changes associated with neural activity. These results suggest new ways to evaluate MRI signal changes within white matter.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.