Evidence map›Paper›PMID 26477300›Full record

ReviewNeurobiology of disease2016

Controversies in preterm brain injury.

Anna A Penn, Pierre Gressens, Bobbi Fleiss, Stephen A Back, Vittorio Gallo

Abstract readReview
In one paragraph

Review in Neurobiology of disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  19. Delayed intranasal infusion of human amnion epithelial cells improves white matter maturation after asphyxia in preterm fetal sheep.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anna A PennFetal Medicine Institute, Neonatology, Center for Neuroscience Research, Children's National Medical Center, George Washington University School of Medicine, Washington, DC, USA. Electronic address: apenn@childrensnational.org.
Pierre GressensUniv Paris Diderot, Sorbonne Paris Cité, UMRS 1141, Paris, France; Centre for the Developing Brain, King's College, St Thomas' Campus, London, UK.
Bobbi FleissUniv Paris Diderot, Sorbonne Paris Cité, UMRS 1141, Paris, France; Centre for the Developing Brain, King's College, St Thomas' Campus, London, UK.
Stephen A BackDepartments of Pediatrics and Neurology, Oregon Health & Science University, Portland, OR, USA.
Vittorio GalloCenter for Neuroscience Research, Children's National Medical Center, George Washington University School of Medicine, Washington, DC, USA.

Funding

NEUROIMAGING COREP30HD040677 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2001 to 2015
$15.9M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI GAILLARD, WILLIAM DAVIS · 2016 to 2020
$5.9M
Role of Extracellular Matrix in Hypoxic-Ischemic Perinatal White Matter InjuryR01NS054044 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BACK, STEPHEN ARTHUR · 2006 to 2021
$4.8M
Novel Roles of Placental Allopregnanolone in Brain Development and InjuryR01HD092593 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ANNA A PENN · 2017 to 2026
$3.9M
A Common Glial-Neuronal Progenitor in Postnatal BrainR01NS045702 · NINDS · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2004 to 2014
$3.7M
Cellular Mechanisms of Fetal White Matter InjuryR01NS045737 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BACK, STEPHEN ARTHUR · 2003 to 2019
$3.7M
Cellular mechanisms of fetal white matter injuryR37NS045737 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI BACK, STEPHEN ARTHUR · 2007 to 2013
$2.7M
Fetal Brain Damage: A Placental DisorderDP2OD006457 · OD · STANFORD UNIVERSITY · PI PENN, ANNA A · 2009 to 2009
$2.4M
NICHD NIH HHS P30 HD040677NICHD NIH HHS R01 HD092593NICHD NIH HHS U54 HD090257NIH HHS DP2 OD006457NINDS NIH HHS R01 NS045702NINDS NIH HHS R01 NS045737NINDS NIH HHS R01 NS054044NINDS NIH HHS R37 NS045737
6 · The paper itself

Abstract

In this review, we highlight critical unresolved questions in the etiology and mechanisms causing preterm brain injury. Involvement of neurons, glia, endogenous factors and exogenous exposures is considered. The structural and functional correlates of interrupted development and injury in the premature brain are under active investigation, with the hope that the cellular and molecular mechanisms underlying developmental abnormalities in the human preterm brain can be understood, prevented or repaired.

Indexed as

AnimalsBrainBrain InjuriesHumansBrain developmentNeuroimagingPreterm brain injuryWhite matter injury

Identifiers

PMID26477300
PMCPMC4842157

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.