ReviewMethods in enzymology2015
In Vivo pO2 Imaging of Tumors: Oxymetry with Very Low-Frequency Electron Paramagnetic Resonance.
Review in Methods in enzymology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed.
- Compensator-based small animal IMRT enables conformal preclinical dose painting: application to tumor hypoxia.Scientific reports · 2025Article
- Accelerated EPR imaging using deep learning denoising.Magnetic resonance in medicine · 2025Article
- Assessment of blood-brain barrier leakage and brain oxygenation in Connexin-32 knockout mice with systemic neuroinflammation using pulse electron paramagnetic resonance imaging techniques.Magnetic resonance in medicine · 2024Article
- SOX71, A Biocompatible Succinyl Derivative of the Triarylmethyl Radical OX071 for In Vivo Quantitative Oxygen Mapping Using Electron Paramagnetic Resonance.Molecular imaging and biology · 2024Article
- Sensitive simultaneous measurements of oxygenation and extracellular pH by EPR using a stable monophosphonated trityl radical and lithium phthalocyanine.Free radical biology & medicine · 2024Article
- Evaluation of a deuterated triarylmethyl spin probe for in vivo RMagnetic resonance in medicine · 2024Article
- HIF-stabilizing biomaterials: from hypoxia-mimicking to hypoxia-inducing.Materials advances · 2023Review
- Evaluation of a deuterated triarylmethyl spin probe for in vivobioRxiv : the preprint server for biology · 2023Article
- Recent advances in microresonators and supporting instrumentation for electron paramagnetic resonance spectroscopy.The Review of scientific instruments · 2022Article
- EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells.Molecules (Basel, Switzerland) · 2022Article
- Molecular oxygen as a probe molecule in EPR spin-labeling studies of membrane structure and dynamics.Oxygen (Basel, Switzerland) · 2022Article
- The Role of Imaging Biomarkers to Guide Pharmacological Interventions Targeting Tumor Hypoxia.Frontiers in pharmacology · 2022Review
- Spin-spin interaction and relaxation in two trityl-nitroxide diradicals.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021Article
- Biological Applications of Electron Paramagnetic Resonance Viscometry Using aMolecules (Basel, Switzerland) · 2021Article
- An inverse-breathing encapsulation system for cell delivery.Science advances · 2021Article
- Synthetic promoters to induce immune-effectors into the tumor microenvironment.Communications biology · 2021Article
- Article
- Chemical exchange induced Hahn echo modulation in pulsed electron paramagnetic resonance experiment.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2020Article
- Rapid-scan EPR imaging of a phantom comprised of species with different linewidths and relaxation times.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2019Article
- Dextran-conjugated tetrathiatriarylmethyl radicals as biocompatible spin probes for EPR spectroscopy and imaging.Bioorganic & medicinal chemistry letters · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
For over a century, it has been known that tumor hypoxia, regions of a tumor with low levels of oxygenation, are important contributors to tumor resistance to radiation therapy and failure of radiation treatment of cancer. Recently, using novel pulse electron paramagnetic resonance (EPR) oxygen imaging, near absolute images of the partial pressure of oxygen (pO2) in tumors of living animals have been obtained. We discuss here the means by which EPR signals can be obtained in living tissues and tumors. We review development of EPR methods to image the pO2 in tumors and the potential for the pO2 image acquisition in human subjects.
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