ArticleDocumenta ophthalmologica. Advances in ophthalmology2015
Macular function measured by binocular mfERG and compared with macular structure in healthy children.
Article in Documenta ophthalmologica. Advances in ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Characterization of functional and structural impairments in best vitelliform macular dystrophy using visual electrophysiology and optical coherence tomography in pediatric and adult patients.Documenta ophthalmologica. Advances in ophthalmology · 2026Article
- What can visual electrophysiology tell about possible visual-field defects in paediatric patients.Eye (London, England) · 2021Review
- Impact of contact lens materials on the mfERG response of the human retina.Documenta ophthalmologica. Advances in ophthalmology · 2020Article
- Multifocal ERG Responses in Subjects With a History of Preterm Birth.Investigative ophthalmology & visual science · 2017Article
- Macular function in preterm children at school age.Documenta ophthalmologica. Advances in ophthalmology · 2016Article
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Authors and funding
5 authors.
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Abstract
purposeTo create normative data in children from binocular multifocal ERG (mfERG) recordings and compare results with the macular thickness.
methodsForty-nine 5- to 15-year-old healthy, full-term children were examined with Espion Multifocal System, using DTL electrodes. The stimulus matrix consisted of 37 hexagonal elements. Amplitudes, implicit times and response densities (presented in three rings) of the first-order component P1 were analyzed. Measurements of macular thickness were performed with spectral-domain Cirrus OCT.
resultsThere were no significant differences between right and left eyes regarding mfERG recordings. Median P1 implicit times of Rings 1-3 of the 46 right eyes were 30.0, 30.0 and 30.8 ms and response densities 20.5, 10.9 and 7.6 nV/deg(2), respectively. Implicit time was longer in boys than in girls (p = 0.009, 0.039, 0.005 in Rings 1-3) and was correlated with age (r s = 0.417, 0.316, 0.274 in Rings 1-3). Implicit time in Ring 1 correlated significantly with the inner circle of the OCT measurements (p = 0.014).
conclusionBinocular mfERG with DTL electrodes is a reliable test of the central macular function in children and correlates with macular structure. As previously not shown, there was a significant difference in implicit time between boys and girls.
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