Evidence map›Paper›PMID 26476835›Full record

Observational studyObesity surgery2016

Monitoring of Diabetic Retinopathy in relation to Bariatric Surgery: a Prospective Observational Study.

Troels Brynskov, Caroline Schmidt Laugesen, Annette Lykke Svenningsen, Andrea Karen Floyd, Torben Lykke Sørensen

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Troels BrynskovDepartment of Ophthalmology, Copenhagen University Hospital Roskilde, Køgevej 7-13, 4000, Roskilde, Denmark. troels@brynskov.com.ORCID 0000-0002-5250-4257
Caroline Schmidt LaugesenDepartment of Ophthalmology, Copenhagen University Hospital Roskilde, Køgevej 7-13, 4000, Roskilde, Denmark.
Annette Lykke SvenningsenDepartment of Internal Medicine, Copenhagen University Hospital Holbæk, Holbæk, Denmark.
Andrea Karen FloydDepartment of Bariatric Surgery, Copenhagen University Hospital Køge, Køge, Denmark.
Torben Lykke SørensenDepartment of Ophthalmology, Copenhagen University Hospital Roskilde, Køgevej 7-13, 4000, Roskilde, Denmark.
Copenhagen University Hospital · DKRoskilde University · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo investigate the need for closer perioperative monitoring of diabetic retinopathy in patients with type 2 diabetes undergoing bariatric surgery.

methodsProspective observational clinical study of 56 patients with type 2 diabetes undergoing bariatric surgery. The patients were examined with 7-field fundus images and optical coherence tomography scans 2 weeks before and 1, 3, 6 and 12 months after bariatric surgery. Worsening was defined as a two-step change in the Wisconsin Epidemiologic Study of Diabetic Retinopathy scale or appearance or worsening of macular edema. Postoperative changes were analyzed in a mixed model.

resultsSix patients (11 %) had any worsening at any visit, and three (5 %) persisted at 1 year. Of the 24 patients with preoperative retinopathy, 4-13 % worsened and 9-22 % improved, with significant overall improvement at 6 months (p = 0.01). Only one (3%) of the 32 patients without preoperative diabetic retinopathy had a transient worsening at 6 months. No patients developed macular edema, but the whole cohort had a minor increase in center point foveal thickness that peaked 6 months postoperatively. The patients were required to have good glucose control preoperatively where HbA1c was 6.4 ± 1.9 %.

conclusionsDiabetic retinopathy was clinically stable after bariatric surgery, and none of the observed changes would have resulted in a changed screening interval at our center. This supports adherence to regular diabetic retinopathy screening guidelines following bariatric surgery in well-controlled patients. A clinically negligible but statistically significant foveal thickening 6 months postoperatively warrants further study.

Indexed as

Bariatric SurgeryAdultBody Mass IndexDiabetes Mellitus, Type 2Diabetic RetinopathyDisease ProgressionFemaleGlycated HemoglobinHumansLong-Term CareMacular EdemaMaleMass ScreeningMiddle AgedObesity, MorbidPostoperative CareGlycated Hemoglobinhemoglobin A1c protein, humanBariatric surgeryDiabetes complicationsDiabetic retinopathyEarly worseningGastric bypass surgeryGastric sleeve gastrectomy

Identifiers

PMID26476835
OpenAlexW2095830956

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.