Evidence map›Paper›PMID 26476633›Full record

ArticleEuropean journal of nutrition2017

Inhibition of pancreatic cancer cell migration by plasma anthocyanins isolated from healthy volunteers receiving an anthocyanin-rich berry juice.

Sabine Kuntz, Clemens Kunz, Silvia Rudloff

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Article in European journal of nutrition, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Sabine KuntzInstitute of Nutritional Science, Justus Liebig University Giessen, Wilhelmstrasse 20, 35392, Giessen, Germany. Sabine.Kuntz@uni-giessen.de.
Clemens KunzInstitute of Nutritional Science, Justus Liebig University Giessen, Wilhelmstrasse 20, 35392, Giessen, Germany.
Silvia RudloffDepartment of Pediatrics, Justus Liebig University Giessen, Feulgenstrasse 12, 35392, Giessen, Germany.
University of Giessen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePancreatic cancer is an aggressive cancer type, of which the most important characteristics are migration and metastasis. Anthocyanins (ACN) are discussed to be protective phytochemicals; however, up to now only scarce data are available regarding their effects on cancer prevention. In this study, we aimed to determine whether ACN and their metabolites from plasma (PAM), isolated from blood of healthy volunteers after ingestion of an ACN-rich juice, are effective in modulating cancer cell migration in vitro.

methodsPAM were isolated from blood of healthy volunteers (n = 10) after consumption of an ACN-rich berry juice. Before ingestion (PAM

resultsAfter application of PAM

conclusionIt can be assumed that physiologically relevant ACN and their metabolites were able to inhibit pancreatic cancer cell migration in dependency of the phenotype of cells and may thus deserve further attention as potential bioactive phytochemicals in cancer prevention.

Indexed as

AnthocyaninsAntioxidantsApoptosisCell Line, TumorCell MovementCell ProliferationCell SurvivalFruitFruit and Vegetable JuicesHealthy VolunteersHumansMaleMatrix Metalloproteinase 2Matrix Metalloproteinase 9NF-kappa BPancreatic NeoplasmsAnthocyaninsAntioxidantsMatrix Metalloproteinase 2Matrix Metalloproteinase 9MMP2 protein, humanMMP9 protein, humanNF-kappa BReactive Oxygen SpeciesRNA, MessengerAnthocyaninsGrapes and bilberriesMetalloproteinasesMigrationPancreatic cancer cells

Identifiers

PMID26476633
OpenAlexW1949310406

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.