Evidence map›Paper›PMID 26476540›Full record

ReviewTumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine2016

T cells in tumor microenvironment.

Yağmur Kiraz, Yusuf Baran, Ayten Nalbant

Abstract readReview
PubMed Publisher
In one paragraph

Review in Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. PD-1, FOXP3, and CSF-1R expression in patients with Hodgkin lymphoma and their prognostic value.International journal of clinical and experimental pathology · 2018
    Article
  6. In vitro and in vivo anti-tumor effects of selected platinum(IV) and dinuclear platinum(II) complexes against lung cancer cells.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2017
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yağmur KirazDepartment of Molecular Biology and Genetics, Molecular Immunology and Gene Regulation Laboratory, Izmir Institute of Technology, Urla, 35430, İzmir, Turkey.
Yusuf BaranDepartment of Molecular Biology and Genetics, Molecular Immunology and Gene Regulation Laboratory, Izmir Institute of Technology, Urla, 35430, İzmir, Turkey.
Ayten NalbantDepartment of Molecular Biology and Genetics, Molecular Immunology and Gene Regulation Laboratory, Izmir Institute of Technology, Urla, 35430, İzmir, Turkey. aytennalbant@iyte.edu.tr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tumors progress in a specific area, which supports its development, spreading or shrinking in time with the presence of different factors that effect the fate of the cancer cells. This specialized site is called "tumor microenvironment" and has a composition of heterogenous materials. The immune cells are also residents of this stromal, cancerous, and inflammatory environment, and their types, densities, or functional differences are one of the key factors that mediate the fate of a tumor. T cells as a vital part of the immune system also are a component of tumor microenvironment, and their roles have been elucidated in many studies. In this review, we focused on the immune system components by focusing on T cells and detailed T helper cell subsets in tumor microenvironment and how their behaviors affect either the tumor or the patient's outcome.

Indexed as

Tumor MicroenvironmentAnimalsDendritic CellsDisease ProgressionFibroblastsHumansImmune SystemInflammationLymphocytesMacrophagesMiceNeoplasmsTh17 CellsT-LymphocytesT-Lymphocytes, Helper-InducerTreatment OutcomeCancer immunologyT cellsTh17 cellsT helper cellsTumor microenvironment

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.