Evidence map›Paper›PMID 26476489›Full record

Trial reportJournal of psychiatric research2015

A clinical measure of suicidal ideation, suicidal behavior, and associated symptoms in bipolar disorder: Psychometric properties of the Concise Health Risk Tracking Self-Report (CHRT-SR).

Michael J Ostacher, Andrew A Nierenberg, Dustin Rabideau, Noreen A Reilly-Harrington, Louisa G Sylvia, Alexandra K Gold, Leah W Shesler, Terence A Ketter, Charles L Bowden, Joseph R Calabrese and 5 more

Open access · greenAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of psychiatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

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  15. VitalSignPharmaceuticals (Basel, Switzerland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 10 institutions in 1 country.

Michael J OstacherVA Palo Alto Health Care System, Palo Alto, CA, USA; Department of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA. Electronic address: ostacher@stanford.edu.
Andrew A NierenbergDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Dustin RabideauBiostatistics Center, Massachusetts General Hospital, Boston, MA, USA.
Noreen A Reilly-HarringtonDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Louisa G SylviaDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
Alexandra K GoldDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Leah W SheslerDepartment of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.
Terence A KetterDepartment of Psychiatry & Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, USA.
Charles L BowdenDepartment of Psychiatry, University of Texas Health Science Center, San Antonio, TX, USA.
Joseph R CalabreseBipolar Disorders Research Center, University Hospital's Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
Edward S FriedmanDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Dan V IosifescuDepartment of Psychiatry, Icahn School of medicine at Mount Sinai, New York, NY, USA.
Michael E ThaseDepartment of Psychiatry, University of Pennsylvania School of Medicine, USA.
Andrew C LeonBiostatistics in Psychiatry & Public Health, Weill Cornell Medical College, New York, NY, USA.
Madhukar H TrivediDepartment of Psychiatry, The University of Texas Southwestern Medical Center, USA.
Massachusetts General Hospital · USHarvard University · USStanford University · USCornell University · USIcahn School of Medicine at Mount Sinai · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas Southwestern Medical Center · USUniversity Hospitals Case Medical Center · USUniversity of Pennsylvania · USUniversity of Pittsburgh · US

Funding

TREATMENT OF BIPOLAR DISORDER-278980001N01MH080001 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · 1998 to 2003
$5.3M
NIMH NIH HHS N01 MH080001
6 · The paper itself

Abstract

objectivePeople with bipolar disorder are at high risk of suicide, but no clinically useful scale has been validated in this population. The aim of this study was to evaluate the psychometric properties in bipolar disorder of the 7- and 12-item versions of the Concise Health Risk Tracking Self-Report (CHRT-SR), a scale measuring suicidal ideation, suicidal behavior, and associated symptoms.

methodsThe CHRT was administered to 283 symptomatic outpatients with bipolar I or II disorder who were randomized to receive lithium plus optimized personalized treatment (OPT), or OPT without lithium in a six month longitudinal comparative effectiveness trial. Participants were assessed using structured diagnostic interviews, clinician-rated assessments, and self-report questionnaires.

resultsThe internal consistency (Cronbach α) was 0.80 for the 7-item CHRT-SR and 0.90 for the 12-item CHRT-SR with a consistent factor structure, and three independent factors (current suicidal thoughts and plans, hopelessness, and perceived lack of social support) for the 7-item version. CHRT-SR scores are correlated with measures of depression, functioning, and quality of life, but not with mania scores.

conclusionsThe 7- and 12-item CHRT-SR both had excellent psychometric properties in a sample of symptomatic subjects with bipolar disorder. The scale is highly correlated with depression, functioning, and quality of life, but not with mania. Future research is needed to determine whether the CHRT-SR will be able to predict suicide attempts in clinical practice.

Indexed as

Self ReportSuicideAdultBipolar DisorderFemaleFollow-Up StudiesHumansLithium CompoundsLongitudinal StudiesMalePrecision MedicinePsychometricsPsychotropic DrugsLithium CompoundsPsychotropic DrugsBipolar disorderEvidence-based careMood disordersPsychometricsSuicide

Identifiers

PMID26476489
PMCPMC6778403
OpenAlexW1790589130

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.