Evidence map›Paper›PMID 26476443›Full record

ArticleNucleic acids research2016

CauloBrowser: A systems biology resource for Caulobacter crescentus.

Keren Lasker, Jared M Schrader, Yifei Men, Tyler Marshik, David L Dill, Harley H McAdams, Lucy Shapiro

Open access · goldAbstract read
In one paragraph

Article in Nucleic acids research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Multilayered control of chromosome replication inBiochemical Society transactions · 2019
    Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Dynamic translation regulation in Caulobacter cell cycle control.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keren LaskerDepartment of Developmental Biology, Stanford University, Stanford, CA 94305, USA kerenl@stanford.edu.
Jared M SchraderDepartment of Developmental Biology, Stanford University, Stanford, CA 94305, USA.
Yifei MenDepartment of Computer Science, Stanford University, Stanford, CA 94305, USA.
Tyler MarshikDepartment of Developmental Biology, Stanford University, Stanford, CA 94305, USA.
David L DillDepartment of Computer Science, Stanford University, Stanford, CA 94305, USA.
Harley H McAdamsDepartment of Developmental Biology, Stanford University, Stanford, CA 94305, USA.
Lucy ShapiroDepartment of Developmental Biology, Stanford University, Stanford, CA 94305, USA.
Stanford University · US

Funding

REGULATION OF DIFFERENTIATION IN CAULOBACTERR01GM032506 · NIGMS · YESHIVA UNIVERSITY · PI SHAPIRO, LUCILLE · 1985 to 2014
$7.1M
DEVELOPMENT CONTROL OF DNA REPLICATION IN CAULOBACTERR01GM051426 · NIGMS · STANFORD UNIVERSITY · PI SHAPIRO, LUCILLE · 1994 to 2013
$3.8M
A systems approach to understand translation and sRNA-mediated gene regulation inF32GM100732 · NIGMS · STANFORD UNIVERSITY · PI SCHRADER, JARED MICHAEL · 2012 to 2014
$150k
NIGMS NIH HHS F32 GM100732NIGMS NIH HHS R01 GM32506NIGMS NIH HHS R01 GM51426
6 · The paper itself

Abstract

Caulobacter crescentus is a premier model organism for studying the molecular basis of cellular asymmetry. The Caulobacter community has generated a wealth of high-throughput spatiotemporal databases including data from gene expression profiling experiments (microarrays, RNA-seq, ChIP-seq, ribosome profiling, LC-ms proteomics), gene essentiality studies (Tn-seq), genome wide protein localization studies, and global chromosome methylation analyses (SMRT sequencing). A major challenge involves the integration of these diverse data sets into one comprehensive community resource. To address this need, we have generated CauloBrowser (www.caulobrowser.org), an online resource for Caulobacter studies. This site provides a user-friendly interface for quickly searching genes of interest and downloading genome-wide results. Search results about individual genes are displayed as tables, graphs of time resolved expression profiles, and schematics of protein localization throughout the cell cycle. In addition, the site provides a genome viewer that enables customizable visualization of all published high-throughput genomic data. The depth and diversity of data sets collected by the Caulobacter community makes CauloBrowser a unique and valuable systems biology resource.

Indexed as

Databases, GeneticSystems BiologyBacterial ProteinsCaulobacter crescentusCell CycleChromosomes, BacterialGene Expression ProfilingGenome, BacterialBacterial Proteins

Identifiers

PMID26476443
PMCPMC4702786
OpenAlexW2207462097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.