Evidence map›Paper›PMID 26475982›Full record

ArticleAnnals of epidemiology2015

Reproductive and lifestyle risk factors and mammographic density in Mexican women.

Megan S Rice, Kimberly A Bertrand, Martin Lajous, Rulla M Tamimi, Gabriela Torres, Ruy López-Ridaura, Isabelle Romieu

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03920098 (The Chilean Maternal and Infant Nutrition Cohort Study II), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03920098 unknown statusnot on this mapstarted 2019, after this paper: background citation

The Chilean Maternal and Infant Nutrition Cohort Study II

TypeobservationalSponsorInstituto de Nutrición y Tecnología de los AlimentosRan2019 to 2023Enrolled1,927ConditionsBreast Density, Body Composition, Nutritional Status, Mental Health IssueArmsNutrition and mental health during pregnancy
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Reproductive Factors Related to Childbearing and a Novel Automated Mammographic Measure, V.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  9. Article
  10. Article
  11. Breastfeeding and Mammographic Breast Density: A Cross-sectional Study.Cancer prevention research (Philadelphia, Pa.) · 2023
    Article
  12. Article
  13. Article
  14. A review of menopause nomenclature.Reproductive health · 2022
    Review
  15. Article
  16. The epidemiologic factors associated with breast density: A review.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Review
  17. Article
  18. Alcohol's Effects on Breast Cancer in Women.Alcohol research : current reviews · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Megan S RiceChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Kimberly A BertrandChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Martin LajousCenter for Research on Population Health, National Institute of Public Health, Mexico; Center for Research in Epidemiology and Population Health (CESP), Inserm (Institut National de la Santé et de la Recherche Médicale), U1018, Villejuif, France; Department of Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA. Electronic address: mlajous@insp.mx.
Rulla M TamimiChanning Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA.
Gabriela TorresCenter for Research on Population Health, National Institute of Public Health, Mexico.
Ruy López-RidauraCenter for Research on Population Health, National Institute of Public Health, Mexico.
Isabelle RomieuNutrition and Metabolism Section, International Agency for Research on Cancer, Lyon, France.
Harvard University · USBrigham and Women's Hospital · USCentre International de Recherche sur le Cancer · FRInserm · FR

Funding

Training Program in Cancer EpidemiologyT32CA009001 · NCI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI A. Heather Eliassen, Meir Stampfer · 1985 to 2026
$17.3M
NCI NIH HHS T32 CA009001NCI NIH HHS T32 CA09001World Health Organization 001
6 · The paper itself

Abstract

purposeSeveral breast cancer risk factors have been consistently associated with mammographic density (MD); however, data are limited for Hispanic women.

methodsWe examined data from 1007 premenopausal and 600 postmenopausal women in the Mexican Teachers' Cohort. Multivariable linear regression was used to estimate associations between risk factors and MD.

resultsAmong premenopausal women, age, current body mass index (BMI), BMI at age 18 years, and weight change since age 18 years were inversely associated with percent MD, whereas benign breast disease, alcohol intake, and breastfeeding 12 months or more were associated with higher percent MD. Among postmenopausal women, age, current BMI, BMI at age 18 years, weight change since age 18 years, and speaking or having parents who speak an indigenous language were inversely associated with percent MD, whereas benign breast disease and greater age at natural menopause were positively associated with percent MD. Other breast cancer risk factors, such as age at menarche, parity, and age at first pregnancy, were not significantly associated with density in either premenopausal or postmenopausal women.

conclusionsResults from the Mexican Teachers' Cohort are generally consistent with predictors of mammographic density observed in primarily non-Hispanic white populations; however, certain risk factors (e.g., parity) were not significantly associated with MD.

Indexed as

Life StyleMammographyReproductive HistoryAdultAge FactorsBody Mass IndexBreastBreast DensityBreast NeoplasmsCohort StudiesFemaleHumansMammary Glands, HumanMexicoMiddle AgedMultivariate AnalysisBreast cancerMammographic densityMexico

Identifiers

PMID26475982
PMCPMC4791972
OpenAlexW2170013545

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.