ArticleSocial cognitive and affective neuroscience2016
Differential serotonergic innervation of the amygdala in bonobos and chimpanzees.
Article in Social cognitive and affective neuroscience, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 59 citations in OpenAlex.
- Great Ape Childhoods: Social and Spatial Pathways to Independence in Bonobo and Chimpanzee Infants.Developmental science · 2026Article
- Distribution of Serotonergic Transporter Innervation in the Nucleus Accumbens and Ventral Pallidum Is Highly Conserved Among Primates.The Journal of comparative neurology · 2025Article
- Inhibitory Systems in Brain Evolution: Pathways of Vulnerability in Neurodevelopmental Disorders.Brain, behavior and evolution · 2025Review
- Evolutionary scaling and cognitive correlates of primate frontal cortex microstructure.Brain structure & function · 2024Article
- Elephants as an animal model for self-domestication.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Evaluating Self-Directed Behaviours and Their Association with Emotional Arousal across Two Cognitive Tasks in Bonobos (Animals : an open access journal from MDPI · 2022Article
- Differences in the mutual eye gaze of bonobos (Pan paniscus) and chimpanzees (Pan troglodytes).Journal of comparative psychology (Washington, D.C. : 1983) · 2020Article
- Serotonergic innervation of the amygdala is increased in autism spectrum disorder and decreased in Williams syndrome.Molecular autism · 2020Article
- DHEAS and Human Development: An Evolutionary Perspective.Frontiers in endocrinology · 2020Article
- Human Social Evolution: Self-Domestication or Self-Control?Frontiers in psychology · 2020Article
- Human-specific mutations in VMAT1 confer functional changes and multi-directional evolution in the regulation of monoamine circuits.BMC evolutionary biology · 2019Article
- Serotonergic innervation of the human amygdala and evolutionary implications.American journal of physical anthropology · 2019Article
- Primate mosaic brain evolution reflects selection on sensory and cognitive specialization.Nature ecology & evolution · 2019Article
- Serotonin Receptor 1A Variation Is Associated with Anxiety and Agonistic Behavior in Chimpanzees.Molecular biology and evolution · 2019Article
- Nicotinamide as Independent Variable for Intelligence, Fertility, and Health: Origin of Human Creative Explosions?International journal of tryptophan research : IJTR · 2019Review
- Williams Syndrome, Human Self-Domestication, and Language Evolution.Frontiers in psychology · 2019Article
- Positive and balancing selection onEvolution letters · 2018Article
- A neurochemical hypothesis for the origin of hominids.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Maximizing Explanatory Power in Stereological Data Collection: A Protocol for Reliably Integrating Optical Fractionator and Multiple Immunofluorescence Techniques.Frontiers in neuroanatomy · 2018Article
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7 authors at 6 institutions in 1 country.
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Abstract
Humans' closest living relatives are bonobos (Pan paniscus) and chimpanzees (Pan troglodytes), yet these great ape species differ considerably from each other in terms of social behavior. Bonobos are more tolerant of conspecifics in competitive contexts and often use sexual behavior to mediate social interactions. Chimpanzees more frequently employ aggression during conflicts and actively patrol territories between communities. Regulation of emotional responses is facilitated by the amygdala, which also modulates social decision-making, memory and attention. Amygdala responsiveness is further regulated by the neurotransmitter serotonin. We hypothesized that the amygdala of bonobos and chimpanzees would differ in its neuroanatomical organization and serotonergic innervation. We measured volumes of regions and the length density of serotonin transporter-containing axons in the whole amygdala and its lateral, basal, accessory basal and central nuclei. Results showed that accessory basal nucleus volume was larger in chimpanzees than in bonobos. Of particular note, the amygdala of bonobos had more than twice the density of serotonergic axons than chimpanzees, with the most pronounced differences in the basal and central nuclei. These findings suggest that variation in serotonergic innervation of the amygdala may contribute to mediating the remarkable differences in social behavior exhibited by bonobos and chimpanzees.
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