Evidence map›Paper›PMID 26475847›Full record

SynthesisPeritoneal dialysis international : journal of the International Society for Peritoneal Dialysis

Association of Body Mass Index With Mortality in Peritoneal Dialysis Patients: A Systematic Review and Meta-Analysis.

Seyed-Foad Ahmadi, Golara Zahmatkesh, Elani Streja, Rajnish Mehrotra, Connie M Rhee, Csaba P Kovesdy, Daniel L Gillen, Emad Ahmadi, Gregg C Fonarow, Kamyar Kalantar-Zadeh

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 4 pooled it
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 4 syntheses or guidelines pooled it, 58 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Seyed-Foad AhmadiHarold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, California, USA Department of Population Health and Disease Prevention, Program in Public Health, University of California Irvine, Irvine, California, USA.
Golara ZahmatkeshHarold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, California, USA.
Elani StrejaHarold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, California, USA Veterans Affairs Long Beach Healthcare System, Long Beach, California, USA.
Rajnish MehrotraKidney Research Institute and Division of Nephrology, University of Washington, Seattle, Washington, USA.
Connie M RheeHarold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, California, USA.
Csaba P KovesdyMemphis Veterans Affairs Medical Center, Memphis, Tennessee, USA Division of Nephrology, University of Tennessee Health Science Center, Memphis, Tennessee, USA.
Daniel L GillenDepartment of Population Health and Disease Prevention, Program in Public Health, University of California Irvine, Irvine, California, USA Department of Statistics, Donald Bren School of Information and Computer Sciences, University of California Irvine, Irvine, California, USA Department of Epidemiology, UCLA School of Public Health, Los Angeles, California, USA.
Emad AhmadiDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Gregg C FonarowDivision of Cardiology, UCLA David Geffen School of Medicine, Los Angeles, California, USA.
Kamyar Kalantar-ZadehHarold Simmons Center for Kidney Disease Research and Epidemiology, Division of Nephrology and Hypertension, University of California Irvine Medical Center, Orange, California, USA Department of Population Health and Disease Prevention, Program in Public Health, University of California Irvine, Irvine, California, USA Veterans Affairs Long Beach Healthcare System, Long Beach, California, USA Department of Epidemiology, UCLA School of Public Health, Los Angeles, California, USA kkz@uci.edu.
University of California, Irvine Medical Center · USUCLA Health · USHarvard University · USUniversity of California, Irvine · USUniversity of California, Los Angeles · USUniversity of Tennessee Health Science Center · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelled♦

backgroundAlthough higher body mass index (BMI) is associated with better outcomes in hemodialysis patients, the relationship in peritoneal dialysis (PD) patients is less clear. We aimed to synthesize the results from all large and high-quality studies to examine whether underweight, overweight, or obesity is associated with any significantly different risk of death in peritoneal dialysis patients. ♦

methodsWe searched MEDLINE, EMBASE, Web of Science, CINAHL, and Cochrane CENTRAL, and screened 7,123 retrieved studies for inclusion. Two investigators independently selected the studies using predefined criteria and assessed each study's quality using the Newcastle-Ottawa Quality Assessment Scale. We meta-analyzed the results of the largest studies with no overlap in their data sources. ♦

resultsWe included 9 studies (n = 156,562) in the systematic review and 4 studies in the meta-analyses. When examined without stratifying studies by follow-up duration, the results of the studies were inconsistent. Hence, we pooled the study results stratified based upon their follow-up durations, as suggested by a large study, and observed that being underweight was associated with higher 1-year mortality but had no significant association with 2- and 3- to 5-year mortalities. In contrast, being overweight or obese was associated with lower 1-year mortality but it had no significant association with 2-, and 3- to 5-year mortalities. ♦

conclusionOver the short-term, being underweight was associated with higher mortality and being overweight or obese was associated with lower mortality. The associations of body mass with mortality were not significant over the long-term.

Indexed as

Body Mass IndexPeritoneal DialysisHumansKidney Failure, ChronicObesityThinnessBody mass indexmeta-analysismortalityobesity paradoxperitoneal dialysis

Identifiers

PMID26475847
PMCPMC4881795
OpenAlexW2341726831

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.